Comparative study between efficacy of dexamethasone-prostaglandin-receptal combination and mechanical correction in uterine torsion cases in Egyptian buffalo-cows (Bubalus bubalis)

• Published in: BMC veterinary research 2023-07, Vol.19 (1), p.92-92, Article 92
• Main Authors: Khalphallah, Arafat, Elmeligy, Enas, Al-Daek, Taher, Hussein, Hassan A, Mohamed, Ragab H, Sabra, Mahmoud S, Zakaria, Asem Mohammed, Khalifa, Marwa I, Mohammed, Haitham H, Khesruf, Khaled A, Ghallab, Rezk Said
• Format: Article
• Language: English
• Subjects: Animals; Birth weight; Body weight; Buffalo-cows; Care and treatment; Cattle; Cervix; Childbirth & labor; Clinical findings; Comparative analysis; Cosmetics industry; Cow's milk; Dexamethasone; Dexamethasone-prostaglandin-receptal combination; Diagnosis; Diseases; Dosage and administration; Drug dosages; Growth; Milk; Ovaries; Placenta; Placental characterization; Pregnancy; Pregnancy, Complications of; Prostaglandins; Somatic cell count; Steroids; Uterine torsion; Uterus; Vagina; Variation
• ISSN: 1746-6148; 1746-6148
• DOI: 10.1186/s12917-023-03651-y

According to reports, the majority of domesticated species exhibited uterine torsion. It was occasionally noted as a cause of dystocia in buffaloes. The uterus might twist more frequently late in pregnancy because of certain animal traits. The current research monitored the clinical findings and laboratory assays associated with uterine torsion cases in pregnant buffalo-cows through comparing between normal labored buffalo-cows (Norm-Lab ; n = 20), mechanically corrected uterine torsed animals without medicament interference (UtrTors ; n = 160), and mechanically corrected uterine torsed animals with medicament interference (UtrTors-Med ; n = 40) through focusing on placental characterization, calves body weight, milk constituents and milk somatic cell count (SCC) in normal labored buffaloes and uterine torsed ones. Through clinical and laboratory investigations of these buffaloes (N = 220) had been conducted 3 times; 7 h pre-calving and post calving (Post uterine correction) i.e. 48 and 96 h. Uterine torsion prevalence parameters, placental characterization, calves body weight, milk constituents and milk somatic cell counts were evaluated in normal labored buffaloes and uterine torsed ones. The study concluded pre-calving remarkable variations in clinical findings, leukogram picture, calf birth weight and some placental characterization parameters between Norm-Lab and each of UtrTors and UtrTors-Med whereas these variations disappeared post-partum as a result to either only mechanical correction or mechanical correction plus medicaments interference. No pre-or post-calving significant changes between UtrTors and UtrTors-Med except for the abnormal clinical findings were more representative in UtrTors-Med than those in UtrTors particularly pre-calving. The applied pre-calving therapeutic regimen including dexamethasone-prostaglandin-receptal combination had a powerful potential efficacy that induced vaginal delivery of calves in UtrTors-Med as well as prepartum mechanical correction of torsed uterus approved higher efficacy in UtrTors . The applied prepartum mechanical correction of torsed uterus and/or pre-calving therapeutic regimen as well as subsequent post-calving, post uterine correction applied medicament treatment accelerated rapid recovery of affected buffalo-cows through achieving rapid restoring of their physiological parameters. Buffalo-cow's milk composition, milk pH and milk SCC were not affected whereas no significant variations were reported