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A bio-inspired two-layer sensing structure of polypeptide and multiple-walled carbon nanotube to sense small molecular gases
In this paper, we propose a bio-inspired, two-layer, multiple-walled carbon nanotube (MWCNT)-polypeptide composite sensing device. The MWCNT serves as a responsive and conductive layer, and the nonselective polypeptide (40 mer) coating the top of the MWCNT acts as a filter into which small molecular...
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Published in: | Sensors (Basel, Switzerland) Switzerland), 2015-03, Vol.15 (3), p.5390-5401 |
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creator | Wang, Li-Chun Su, Tseng-Hsiung Ho, Cheng-Long Yang, Shang-Ren Chiu, Shih-Wen Kuo, Han-Wen Tang, Kea-Tiong |
description | In this paper, we propose a bio-inspired, two-layer, multiple-walled carbon nanotube (MWCNT)-polypeptide composite sensing device. The MWCNT serves as a responsive and conductive layer, and the nonselective polypeptide (40 mer) coating the top of the MWCNT acts as a filter into which small molecular gases pass. Instead of using selective peptides to sense specific odorants, we propose using nonselective, peptide-based sensors to monitor various types of volatile organic compounds. In this study, depending on gas interaction and molecular sizes, the randomly selected polypeptide enabled the recognition of certain polar volatile chemical vapors, such as amines, and the improved discernment of low-concentration gases. The results of our investigation demonstrated that the polypeptide-coated sensors can detect ammonia at a level of several hundred ppm and barely responded to triethylamine. |
doi_str_mv | 10.3390/s150305390 |
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The MWCNT serves as a responsive and conductive layer, and the nonselective polypeptide (40 mer) coating the top of the MWCNT acts as a filter into which small molecular gases pass. Instead of using selective peptides to sense specific odorants, we propose using nonselective, peptide-based sensors to monitor various types of volatile organic compounds. In this study, depending on gas interaction and molecular sizes, the randomly selected polypeptide enabled the recognition of certain polar volatile chemical vapors, such as amines, and the improved discernment of low-concentration gases. The results of our investigation demonstrated that the polypeptide-coated sensors can detect ammonia at a level of several hundred ppm and barely responded to triethylamine.</description><identifier>ISSN: 1424-8220</identifier><identifier>EISSN: 1424-8220</identifier><identifier>DOI: 10.3390/s150305390</identifier><identifier>PMID: 25751078</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Ammonia ; Ammonia - chemistry ; Ammonia - isolation & purification ; bio-inspired ; Biosensing Techniques - instrumentation ; Carbon ; Carbon nanotubes ; gas sensing ; Gases ; Gases - chemistry ; Gases - isolation & purification ; Ligands ; Molecular gases ; Monitors ; multiple-walled carbon nanotube (MWCNT) ; Nanotubes, Carbon - chemistry ; Odorants ; Organic compounds ; Peptides - chemistry ; Polymers ; polypeptide ; Polypeptides ; Semiconductors ; Sensors ; two-layer structure ; VOCs ; Volatile organic compounds ; Volatile Organic Compounds - chemistry ; Volatile Organic Compounds - isolation & purification</subject><ispartof>Sensors (Basel, Switzerland), 2015-03, Vol.15 (3), p.5390-5401</ispartof><rights>Copyright MDPI AG 2015</rights><rights>2015 by the authors; licensee MDPI, Basel, Switzerland. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c575t-6c020c152a9edd67f48dba6e442aefa5b543c002ae7af03c18c54eb6249f3ccc3</citedby><cites>FETCH-LOGICAL-c575t-6c020c152a9edd67f48dba6e442aefa5b543c002ae7af03c18c54eb6249f3ccc3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/1672897933/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1672897933?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793,75126</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25751078$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Li-Chun</creatorcontrib><creatorcontrib>Su, Tseng-Hsiung</creatorcontrib><creatorcontrib>Ho, Cheng-Long</creatorcontrib><creatorcontrib>Yang, Shang-Ren</creatorcontrib><creatorcontrib>Chiu, Shih-Wen</creatorcontrib><creatorcontrib>Kuo, Han-Wen</creatorcontrib><creatorcontrib>Tang, Kea-Tiong</creatorcontrib><title>A bio-inspired two-layer sensing structure of polypeptide and multiple-walled carbon nanotube to sense small molecular gases</title><title>Sensors (Basel, Switzerland)</title><addtitle>Sensors (Basel)</addtitle><description>In this paper, we propose a bio-inspired, two-layer, multiple-walled carbon nanotube (MWCNT)-polypeptide composite sensing device. 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The results of our investigation demonstrated that the polypeptide-coated sensors can detect ammonia at a level of several hundred ppm and barely responded to triethylamine.</description><subject>Ammonia</subject><subject>Ammonia - chemistry</subject><subject>Ammonia - isolation & purification</subject><subject>bio-inspired</subject><subject>Biosensing Techniques - instrumentation</subject><subject>Carbon</subject><subject>Carbon nanotubes</subject><subject>gas sensing</subject><subject>Gases</subject><subject>Gases - chemistry</subject><subject>Gases - isolation & purification</subject><subject>Ligands</subject><subject>Molecular gases</subject><subject>Monitors</subject><subject>multiple-walled carbon nanotube (MWCNT)</subject><subject>Nanotubes, Carbon - chemistry</subject><subject>Odorants</subject><subject>Organic compounds</subject><subject>Peptides - chemistry</subject><subject>Polymers</subject><subject>polypeptide</subject><subject>Polypeptides</subject><subject>Semiconductors</subject><subject>Sensors</subject><subject>two-layer structure</subject><subject>VOCs</subject><subject>Volatile organic compounds</subject><subject>Volatile Organic Compounds - chemistry</subject><subject>Volatile Organic Compounds - isolation & purification</subject><issn>1424-8220</issn><issn>1424-8220</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNkk1rFTEUhgdRbL268QdIwI0Io_m8k9kIpfhRKLjRdTiTOXPNJZOMScZywR9v7K21deUqh-TJw3uS0zTPGX0jRE_fZqaooKqWD5pTJrlsNef04Z36pHmS855SLoTQj5sTrjrFaKdPm59nZHCxdSEvLuFIylVsPRwwkYwhu7AjuaTVljUhiRNZoj8suBQ3IoEwknn1xS0e2yvwvl63kIYYSIAQyzogKfHagyTPFSBz9GhXD4nsIGN-2jyawGd8drNumq8f3n85_9Refv54cX522dqas7RbSzm1THHocRy33ST1OMAWpeSAE6hBSWFrc4AdTFRYpq2SOGy57CdhrRWb5uLoHSPszZLcDOlgIjhzvRHTzkAqzno0Qkk7Kg3V18lebQdKLRcWRqZ1DdFX17uja1mHGUeLoSTw96T3T4L7Znbxh5FSKCa6Knh1I0jx-4q5mNlli95DwLhmw7ZaaaYU-x-09igEFaqiL_9B93FNob5qpTqu-66vf79pXh8pm2LOCafb3Iya37Nk_s5ShV_c7fQW_TM84hfGRcX3</recordid><startdate>20150305</startdate><enddate>20150305</enddate><creator>Wang, Li-Chun</creator><creator>Su, Tseng-Hsiung</creator><creator>Ho, Cheng-Long</creator><creator>Yang, Shang-Ren</creator><creator>Chiu, Shih-Wen</creator><creator>Kuo, Han-Wen</creator><creator>Tang, Kea-Tiong</creator><general>MDPI AG</general><general>MDPI</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>7SP</scope><scope>7TB</scope><scope>7U5</scope><scope>8FD</scope><scope>FR3</scope><scope>L7M</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20150305</creationdate><title>A bio-inspired two-layer sensing structure of polypeptide and multiple-walled carbon nanotube to sense small molecular gases</title><author>Wang, Li-Chun ; Su, Tseng-Hsiung ; Ho, Cheng-Long ; Yang, Shang-Ren ; Chiu, Shih-Wen ; Kuo, Han-Wen ; Tang, Kea-Tiong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c575t-6c020c152a9edd67f48dba6e442aefa5b543c002ae7af03c18c54eb6249f3ccc3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Ammonia</topic><topic>Ammonia - chemistry</topic><topic>Ammonia - isolation & purification</topic><topic>bio-inspired</topic><topic>Biosensing Techniques - instrumentation</topic><topic>Carbon</topic><topic>Carbon nanotubes</topic><topic>gas sensing</topic><topic>Gases</topic><topic>Gases - chemistry</topic><topic>Gases - isolation & purification</topic><topic>Ligands</topic><topic>Molecular gases</topic><topic>Monitors</topic><topic>multiple-walled carbon nanotube (MWCNT)</topic><topic>Nanotubes, Carbon - chemistry</topic><topic>Odorants</topic><topic>Organic compounds</topic><topic>Peptides - chemistry</topic><topic>Polymers</topic><topic>polypeptide</topic><topic>Polypeptides</topic><topic>Semiconductors</topic><topic>Sensors</topic><topic>two-layer structure</topic><topic>VOCs</topic><topic>Volatile organic compounds</topic><topic>Volatile Organic Compounds - chemistry</topic><topic>Volatile Organic Compounds - isolation & purification</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Li-Chun</creatorcontrib><creatorcontrib>Su, Tseng-Hsiung</creatorcontrib><creatorcontrib>Ho, Cheng-Long</creatorcontrib><creatorcontrib>Yang, Shang-Ren</creatorcontrib><creatorcontrib>Chiu, Shih-Wen</creatorcontrib><creatorcontrib>Kuo, Han-Wen</creatorcontrib><creatorcontrib>Tang, Kea-Tiong</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>Electronics & Communications Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Sensors (Basel, Switzerland)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Li-Chun</au><au>Su, Tseng-Hsiung</au><au>Ho, Cheng-Long</au><au>Yang, Shang-Ren</au><au>Chiu, Shih-Wen</au><au>Kuo, Han-Wen</au><au>Tang, Kea-Tiong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A bio-inspired two-layer sensing structure of polypeptide and multiple-walled carbon nanotube to sense small molecular gases</atitle><jtitle>Sensors (Basel, Switzerland)</jtitle><addtitle>Sensors (Basel)</addtitle><date>2015-03-05</date><risdate>2015</risdate><volume>15</volume><issue>3</issue><spage>5390</spage><epage>5401</epage><pages>5390-5401</pages><issn>1424-8220</issn><eissn>1424-8220</eissn><abstract>In this paper, we propose a bio-inspired, two-layer, multiple-walled carbon nanotube (MWCNT)-polypeptide composite sensing device. The MWCNT serves as a responsive and conductive layer, and the nonselective polypeptide (40 mer) coating the top of the MWCNT acts as a filter into which small molecular gases pass. Instead of using selective peptides to sense specific odorants, we propose using nonselective, peptide-based sensors to monitor various types of volatile organic compounds. In this study, depending on gas interaction and molecular sizes, the randomly selected polypeptide enabled the recognition of certain polar volatile chemical vapors, such as amines, and the improved discernment of low-concentration gases. The results of our investigation demonstrated that the polypeptide-coated sensors can detect ammonia at a level of several hundred ppm and barely responded to triethylamine.</abstract><cop>Switzerland</cop><pub>MDPI AG</pub><pmid>25751078</pmid><doi>10.3390/s150305390</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Ammonia Ammonia - chemistry Ammonia - isolation & purification bio-inspired Biosensing Techniques - instrumentation Carbon Carbon nanotubes gas sensing Gases Gases - chemistry Gases - isolation & purification Ligands Molecular gases Monitors multiple-walled carbon nanotube (MWCNT) Nanotubes, Carbon - chemistry Odorants Organic compounds Peptides - chemistry Polymers polypeptide Polypeptides Semiconductors Sensors two-layer structure VOCs Volatile organic compounds Volatile Organic Compounds - chemistry Volatile Organic Compounds - isolation & purification |
title | A bio-inspired two-layer sensing structure of polypeptide and multiple-walled carbon nanotube to sense small molecular gases |
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