Trends in Clinical Characteristics and Short-Term Outcome of HIV-Infected Patients at a Tertiary Care Hospital in South India

Background: Limited information is available on changing trends in HIV positive patients treated with first-line antiretroviral therapy from India. Methods: The clinical characteristics and short-term outcome were compared between a retrospective group enrolled between January 2006 and March 2007 (0...

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Bibliographic Details
Published in:Journal of the International Association of Providers of AIDS Care 2018-01, Vol.17, p.2325958218795886-2325958218795886
Main Authors: Shamanna, Suryanarayana Bettadpura, Matta, Kiran Kumar, Hamide, Abdoul
Format: Article
Language:English
Subjects:
Antiretroviral drugs
Antiretroviral therapy
HIV
Human immunodeficiency virus
Original
Patients
Trends
Tuberculosis
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Summary:Background: Limited information is available on changing trends in HIV positive patients treated with first-line antiretroviral therapy from India. Methods: The clinical characteristics and short-term outcome were compared between a retrospective group enrolled between January 2006 and March 2007 (06-07 group—100 patients) and a prospective group enrolled between February 2011 and March 2012 (10-12 group—85 patients). Results: Median age was 36 and 38 years in 06-07 and 10-12 groups, respectively. Median baseline CD4 count was 146 cells/mL3 in the 10-12 group, and it was not significantly different from that of 06-07 group. Tuberculosis was diagnosed 3 times more commonly in the 10-12 group. The retention proportion at the end of 10 months was 68% in the 10-12 group when compared to that of 59% in the 06-07 group. Conclusion: There was a trend toward improved outcome over the period of time, but the attrition rate remained high.
ISSN:2325-9582
2325-9574
2325-9582
DOI:10.1177/2325958218795886