Caenorhabditis elegans as a Model System for Duchenne Muscular Dystrophy

The nematode worm Caenorhabditis elegans has been used extensively to enhance our understanding of the human neuromuscular disorder Duchenne Muscular Dystrophy (DMD). With new arising clinically relevant models, technologies and treatments, there is a need to reconcile the literature and collate the...

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Bibliographic Details
Published in:International journal of molecular sciences 2021-05, Vol.22 (9), p.4891
Main Authors: Ellwood, Rebecca A., Piasecki, Mathew, Szewczyk, Nathaniel J.
Format: Article
Language:English
Subjects:
Animals
C. elegans
Caenorhabditis elegans
Disease
DMD
Duchenne's muscular dystrophy
dystrophin
Extracellular matrix
Gene expression
Genotype & phenotype
Mammals
muscle
Muscular dystrophy
Mutation
Nematodes
Proteins
Review
Worms
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Summary:The nematode worm Caenorhabditis elegans has been used extensively to enhance our understanding of the human neuromuscular disorder Duchenne Muscular Dystrophy (DMD). With new arising clinically relevant models, technologies and treatments, there is a need to reconcile the literature and collate the key findings associated with this model.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms22094891