Recent advances in understanding acute respiratory distress syndrome

Acute respiratory distress syndrome (ARDS) is characterized by acute diffuse lung injury, which results in increased pulmonary vascular permeability and loss of aerated lung tissue. This causes bilateral opacity consistent with pulmonary edema, hypoxemia, increased venous admixture, and decreased lu...

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Bibliographic Details
Published in:F1000 research 2018, Vol.7, p.263
Main Authors: Wohlrab, Peter, Kraft, Felix, Tretter, Verena, Ullrich, Roman, Markstaller, Klaus, Klein, Klaus Ulrich
Format: Article
Language:English
Subjects:
Airway/Respiratory Physiology
Edema
Hypoxemia
Kinases
Lungs
Mortality
Oxygenation
Patients
Permeability
Respiratory distress syndrome
Respiratory Problems in Critical Care
Respiratory therapy
Review
Ventilators
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Summary:Acute respiratory distress syndrome (ARDS) is characterized by acute diffuse lung injury, which results in increased pulmonary vascular permeability and loss of aerated lung tissue. This causes bilateral opacity consistent with pulmonary edema, hypoxemia, increased venous admixture, and decreased lung compliance such that patients with ARDS need supportive care in the intensive care unit to maintain oxygenation and prevent adverse outcomes. Recently, advances in understanding the underlying pathophysiology of ARDS led to new approaches in managing these patients. In this review, we want to focus on recent scientific evidence in the field of ARDS research and discuss promising new developments in the treatment of this disease.
ISSN:2046-1402
2046-1402
DOI:10.12688/f1000research.11148.1