Major causes of insuline resistance

Causes of insulin resistance can be divided into innate and secondary. There are many reasons for insulin resistance, including genetic mutations like insulin receptor mutations, hormonal and pharmacological or immunological. However insulin resistance is most commonly associated with obesity. Obesi...

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Bibliographic Details
Published in:Journal of education, health and sport health and sport, 2019-09, Vol.9 (9), p.946-952
Main Authors: Ewa Lidia Krzewicka-Romaniuk, Dagna Agnieszka Siedlecka, Anna Pradiuch, Grażyna Wójcicka
Format: Article
Language:English
Subjects:
inflammation
insuline resistance
obesity
Online Access:Get full text
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Summary:Causes of insulin resistance can be divided into innate and secondary. There are many reasons for insulin resistance, including genetic mutations like insulin receptor mutations, hormonal and pharmacological or immunological. However insulin resistance is most commonly associated with obesity. Obesity is associated with a low-grade inflammation of white adipose tissue (WAT) resulting from chronic activation of the innate immune system and which can subsequently lead to insulin resistance, impaired glucose tolerance and diabetes.
ISSN:2391-8306
DOI:10.5281/zenodo.3461607