Macrolide-resistant Mycoplasma pneumoniae in humans, Ontario, Canada, 2010-2011

Antimicrobial drug resistance rates for Mycoplasma pneumoniae was determined in clinical specimens and isolates obtained during 2011-2012 in Ontario, Canada. Of 91 M. pneumoniae drug-resistant specimens, 11 (12.1%) carried nucleotide mutations associated with macrolide resistance in the 23S rRNA gen...

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Bibliographic Details
Published in:Emerging infectious diseases 2013-09, Vol.19 (9), p.1525-1527
Main Authors: Eshaghi, AliReza, Memari, Nader, Tang, Patrick, Olsha, Romy, Farrell, David J, Low, Donald E, Gubbay, Jonathan B, Patel, Samir N
Format: Article
Language:English
Subjects:
Adolescent
Adult
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
antibiotic resistance
bacteria
Bacterial pneumonia
Child
Child, Preschool
community-acquired pneumonia
Dispatch
Distribution
Drug resistance in microorganisms
Drug Resistance, Bacterial
Gene mutations
Genes, Bacterial
Genetic aspects
Genotype
Health aspects
Humans
macrolide resistant
macrolides
Macrolides - pharmacology
Macrolides - therapeutic use
Microbial genetics
Multilocus Sequence Typing
Mycoplasma pneumoniae
Mycoplasma pneumoniae - drug effects
Mycoplasma pneumoniae - genetics
Nucleotides
Ontario - epidemiology
Pneumonia
Pneumonia, Mycoplasma - drug therapy
Pneumonia, Mycoplasma - epidemiology
RNA
Young Adult
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Description
Summary:Antimicrobial drug resistance rates for Mycoplasma pneumoniae was determined in clinical specimens and isolates obtained during 2011-2012 in Ontario, Canada. Of 91 M. pneumoniae drug-resistant specimens, 11 (12.1%) carried nucleotide mutations associated with macrolide resistance in the 23S rRNA gene. None of the M. pneumoniae specimens were resistant to fluoroquinolones or tetracyclines.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1909.121466