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Macrolide-resistant Mycoplasma pneumoniae in humans, Ontario, Canada, 2010-2011
Antimicrobial drug resistance rates for Mycoplasma pneumoniae was determined in clinical specimens and isolates obtained during 2011-2012 in Ontario, Canada. Of 91 M. pneumoniae drug-resistant specimens, 11 (12.1%) carried nucleotide mutations associated with macrolide resistance in the 23S rRNA gen...
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Published in: | Emerging infectious diseases 2013-09, Vol.19 (9), p.1525-1527 |
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container_title | Emerging infectious diseases |
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creator | Eshaghi, AliReza Memari, Nader Tang, Patrick Olsha, Romy Farrell, David J Low, Donald E Gubbay, Jonathan B Patel, Samir N |
description | Antimicrobial drug resistance rates for Mycoplasma pneumoniae was determined in clinical specimens and isolates obtained during 2011-2012 in Ontario, Canada. Of 91 M. pneumoniae drug-resistant specimens, 11 (12.1%) carried nucleotide mutations associated with macrolide resistance in the 23S rRNA gene. None of the M. pneumoniae specimens were resistant to fluoroquinolones or tetracyclines. |
doi_str_mv | 10.3201/eid1909.121466 |
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Of 91 M. pneumoniae drug-resistant specimens, 11 (12.1%) carried nucleotide mutations associated with macrolide resistance in the 23S rRNA gene. 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Of 91 M. pneumoniae drug-resistant specimens, 11 (12.1%) carried nucleotide mutations associated with macrolide resistance in the 23S rRNA gene. None of the M. pneumoniae specimens were resistant to fluoroquinolones or tetracyclines.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>antibiotic resistance</subject><subject>bacteria</subject><subject>Bacterial pneumonia</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>community-acquired pneumonia</subject><subject>Dispatch</subject><subject>Distribution</subject><subject>Drug resistance in microorganisms</subject><subject>Drug Resistance, Bacterial</subject><subject>Gene mutations</subject><subject>Genes, Bacterial</subject><subject>Genetic aspects</subject><subject>Genotype</subject><subject>Health aspects</subject><subject>Humans</subject><subject>macrolide resistant</subject><subject>macrolides</subject><subject>Macrolides - pharmacology</subject><subject>Macrolides - therapeutic use</subject><subject>Microbial genetics</subject><subject>Multilocus Sequence Typing</subject><subject>Mycoplasma pneumoniae</subject><subject>Mycoplasma pneumoniae - drug effects</subject><subject>Mycoplasma pneumoniae - genetics</subject><subject>Nucleotides</subject><subject>Ontario - epidemiology</subject><subject>Pneumonia</subject><subject>Pneumonia, Mycoplasma - drug therapy</subject><subject>Pneumonia, Mycoplasma - epidemiology</subject><subject>RNA</subject><subject>Young Adult</subject><issn>1080-6040</issn><issn>1080-6059</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2013</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNqNkkuL2zAURk1p6TzabZfFUChTiFO9LFubwhD6CMwQ6GsrbuTrRIMtZSy5dP59lSYNE8iiCCQhn3t0kb8se0XJlDNC36NtqCJqShkVUj7JzimpSSFJqZ4e9oKcZRch3BFCU4l6np0xrmRdK3meLW7BDL6zDRYDBhsiuJjfPhi_6SD0kG8cjr13FjC3Ll-PPbgwyRcuwmD9JJ-BgwYmefKSIk30RfashS7gy_16mf349PH77Etxs_g8n13fFEYqEouWGVxyWVHTtEvaKtMCsopXFE1ZVoKJBhpRiiVXAEIua8qUIIoLBbIVTS35ZTbfeRsPd3oz2B6GB-3B6r8HflhpGKI1HWouOQjegqlFI1SZHKaSghlGKrLtIrk-7FybcdljY9DFAboj6fEXZ9d65X9pXlOiiEiCq71g8Pcjhqh7Gwx2HTj0Y9BUsKoSpVLbu97s0BWk1qxrfTKaLa6vuZCEVJKzRBUnqBU6TNd7h61Nx0f89ASfRoO9NScL3h0VJCbi77iCMQQ9__b1_9nFz2P27SN2jdDFdfDdGK134WTHKX0hDNgenpsSvU223idb75KdCl4__kkH_F-U-R_Z4O3T</recordid><startdate>20130901</startdate><enddate>20130901</enddate><creator>Eshaghi, AliReza</creator><creator>Memari, Nader</creator><creator>Tang, Patrick</creator><creator>Olsha, Romy</creator><creator>Farrell, David J</creator><creator>Low, Donald E</creator><creator>Gubbay, Jonathan B</creator><creator>Patel, Samir N</creator><general>U.S. National Center for Infectious Diseases</general><general>Centers for Disease Control and Prevention</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20130901</creationdate><title>Macrolide-resistant Mycoplasma pneumoniae in humans, Ontario, Canada, 2010-2011</title><author>Eshaghi, AliReza ; 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subjects | Adolescent Adult Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use antibiotic resistance bacteria Bacterial pneumonia Child Child, Preschool community-acquired pneumonia Dispatch Distribution Drug resistance in microorganisms Drug Resistance, Bacterial Gene mutations Genes, Bacterial Genetic aspects Genotype Health aspects Humans macrolide resistant macrolides Macrolides - pharmacology Macrolides - therapeutic use Microbial genetics Multilocus Sequence Typing Mycoplasma pneumoniae Mycoplasma pneumoniae - drug effects Mycoplasma pneumoniae - genetics Nucleotides Ontario - epidemiology Pneumonia Pneumonia, Mycoplasma - drug therapy Pneumonia, Mycoplasma - epidemiology RNA Young Adult |
title | Macrolide-resistant Mycoplasma pneumoniae in humans, Ontario, Canada, 2010-2011 |
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