Effect of zinc supplementation on glycemic biomarkers: an umbrella of interventional meta-analyses

Several studies have evaluated the effects of zinc supplementation on glycemic biomarkers in humans and have demonstrated varying results. We systematically evaluated the literature and performed an umbrella meta-analysis of the effects of zinc supplementation on type 2 diabetes biomarkers. A compre...

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Bibliographic Details
Published in:Diabetology and metabolic syndrome 2024-06, Vol.16 (1), p.124-14
Main Authors: Daneshvar, Maziar, Ghaheri, Mohammad, Safarzadeh, Diba, Karimi, Fatemeh, Adib-Hajbagheri, Parisa, Ahmadzade, Mohadese, Haedi, Amir
Format: Article
Language:English
Subjects:
Analysis
Biological markers
Biomarkers
Diabetes
Diabetes mellitus (non-insulin dependent)
Glucose
Glycemic index
Glycemic status
Glycosylated hemoglobin
Homeostasis
Insulin
Insulin resistance
Meta-analysis
Metabolism
Review
Statistical analysis
Supplements
Systematic review
Type 2 diabetes
Zinc
Zinc in the body
Zinc supplementation
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Summary:Several studies have evaluated the effects of zinc supplementation on glycemic biomarkers in humans and have demonstrated varying results. We systematically evaluated the literature and performed an umbrella meta-analysis of the effects of zinc supplementation on type 2 diabetes biomarkers. A comprehensive literature search was conducted in the following databases; PubMed, Embase, Embase, Cochrane Library, Scopus, and Web of Science for studies published up to March 10, 2024. Zinc supplementation was effective in reducing serum FBS (WMD: - 13.58, 95% CI: - 17.38, - 9.77; p 
ISSN:1758-5996
1758-5996
DOI:10.1186/s13098-024-01366-0