Risk Factors of Emergency Room Visits for Bleeding Complications Following Transurethral Procedures in the Treatment of Benign Prostatic Hyperplasia: A Retrospective Cohort Study

• Published in: Clinical interventions in aging 2021-01, Vol.16, p.1747-1756
• Main Authors: Teng, Tzu-Chi, Shao, I-Hung, Hsu, Yu-Chao, Chen, Yu, Tsao, Shu-Han, Kang, Yen-Te, Hsieh, Ming-Li
• Format: Article
• Language: English
• Subjects: Antibiotics; Anticoagulants; Blood clots; Care and treatment; Catheters; clot retention; Cohort analysis; Complications; Complications and side effects; Emergency service; Emergency Service, Hospital; Genital diseases; Hematuria; Hemorrhage; Hospitals; Humans; Hyperplasia; Hypertrophy; Intubation; laser prostatectomy; Laser Therapy; Lasers; Length of stay; Male; Original Research; Patients; Prostate; Prostatectomy, Transurethral; Prostatic Hyperplasia - surgery; Retrospective Studies; Risk Factors; Surgery; transurethral resection of prostate; Transurethral Resection of Prostate - adverse effects; Treatment Outcome; Urinary retention; Urinary tract diseases; Urinary tract infections; Urogenital system; Urological surgery
• ISSN: 1178-1998; 1176-9092; 1178-1998
• DOI: 10.2147/CIA.S329468

Transurethral procedures, including transurethral resection of the prostate (TURP) and laser prostatectomy, are often linked to emergency room (ER) visits for postoperative bleeding. Although some studies have been conducted, the risk factors associated with these ER visits are not completely understood. This retrospective cohort study identified potential risk factors associated with ER visits for postoperative bleeding. Preoperative assessment data and operational and postoperational parameters recorded at Chang Gung Memorial Hospital, Taiwan between December 2015 and January 2017 for patients who underwent elective transurethral procedures were analyzed to identify potential risk factors. The primary endpoint was ER visits for gross hematuria within three months following operation, and the secondary endpoint was ER visits for blood clot-induced urinary retention (clot retention) within three months following operation. A total of 665 patients who underwent elective transurethral procedures were enrolled. The transurethral procedures included monopolar transurethral resection of the prostate (M-TURP), bipolar TURP (B-TURP), greenlight photoselective vaporization of the prostate (PVP), thulium laser enucleation of the prostate (ThuLEP) and thulium laser transurethral vaporesection of the prostate (ThuVARP). Regarding ER visits for clot retention within three months, multivariable logistic regression revealed significantly lower rates of clot retention in patients who received B-TURP than in those who underwent ThuVARP (AOR, 0.18; 95% confidence interval [CI], 0.04-0.82, p = 0.027). Moreover, significantly higher clot retention was observed in patients who underwent two or more rounds of manual irrigation (AOR, 9.51; 95% CI, 1.66-54.43, p = 0.011). Multiple manual irrigations shortly after operation can be considered a novel predictor of postoperative clot retention-related ER visits. Among the transurethral procedures, ThuVARP was associated with a higher risk of clot retention-related ER visits than was B-TURP.