Leukocytosis due to markedly elevated granulocyte-colony stimulating factor levels in a patient with endometrial cancer: Case report and literature review

Highlights • Granulocyte-colony stimulating factor (GCSF) secretion by gynecologic tumors is rare . • Elevations in serum GCSF can be seen in the absence of tumor GSCF secretion . • Extreme leukocytosis is associated with autocrine tumor growth and poor prognosis .

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Bibliographic Details
Published in:Gynecologic oncology reports 2017-05, Vol.20 (C), p.5-8
Main Authors: Clark, Leslie H, Moll, Stephan, Houghton, Damon, O ' Connor, Siohban, Soper, John T
Format: Article
Language:English
Subjects:
Case Report
Endometrial cancer
GCSF
Granulocyte colony stimulating factor
Hematology, Oncology and Palliative Medicine
Leukocytosis
Obstetrics and Gynecology
Prognosis
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Description
Summary:Highlights • Granulocyte-colony stimulating factor (GCSF) secretion by gynecologic tumors is rare . • Elevations in serum GCSF can be seen in the absence of tumor GSCF secretion . • Extreme leukocytosis is associated with autocrine tumor growth and poor prognosis .
ISSN:2352-5789
2352-5789
DOI:10.1016/j.gore.2017.01.007