The Comparative Evaluation of Hospitalized Elderly Patients with COVID-19 from the Onset of the Disease to Recovery and Death in Iran

Background & Objectives: Numerous studies have shown that the risk of death is higher in elderly patients with COVID-19. In Iran, due to the growth of the elderly population and the prevalence of underlying diseases, it is necessary to pay attention to this age group of patients. In this study,...

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Bibliographic Details
Published in:Journal of Advanced Biomedical Sciences 2023-03, Vol.13 (1), p.40-56
Main Authors: Barati, Barat, Kaydani, Masoumeh, Ahmadpour, Fatemeh, Kalantar, Mojtaba, Birgani, Fariba Farhadi
Format: Article
Language:English
Subjects:
chest ct scan
clinical characteristics
covid-19
elderly patients
hounsfield unit
pcr
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Summary:Background & Objectives: Numerous studies have shown that the risk of death is higher in elderly patients with COVID-19. In Iran, due to the growth of the elderly population and the prevalence of underlying diseases, it is necessary to pay attention to this age group of patients. In this study, clinical, radiological, PCR, and laboratory data of elderly patients with COVID-19 were collected and analyzed in two groups of recovered and dead patients.Materials & Methods: This is a retrospective study of 196 consecutive elderly patients with COVID-19 hospitalized from March 21, 2020, to April 3, 2020, and their follow-up until April 23, 2021. Clinical characteristics, laboratory results, PCR, chest CT scans and Hounsfield Unit data were collected and analyzed in two groups of recovered and dead patients. Obtained Data were analyzed using SPSSv22.0 and MATLAB-R2017 software.Results: The results showed that there were no specific symptoms to distinguish the death group from the recovery group. Significant differences were observed between the two groups for red blood cell counts, hemoglobin, MCHC and MCV levels, bilirubin, aminotransferase levels, CRP, white blood cells, serum BNU, creatinine and PT coagulation index. The concentrations of VBG (HCO3) and VBG (PCO2) in the deceased patients suggest compensated respiratory alkalosis. CT sensitivity is 100% for patients in advanced and severe stages of the disease.Conclusion: The patients in the death group had more underlying diseases than the recovered group. COVID-19 patients are more likely to die when they have both diabetes and cardiovascular disease. 
ISSN:2783-1523
2228-5105
2783-1523
DOI:10.18502/jabs.v13i1.12076