Silver Nanoparticles and Mitochondrial Interaction

Nanotechnology has gone through a period of rapid growth, thus leading to the constant increase in the application of engineered nanomaterials in daily life. Several different types of nanoparticles have been engineered to be employed in a wide array of applications due to their high surface to volu...

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Bibliographic Details
Published in:International Journal of Dentistry 2013-01, Vol.2013 (2013), p.111-118
Main Authors: Bressan, Eriberto, Ferroni, Letizia, Gardin, Chiara, Rigo, Chiara, Stocchero, Michele, Vindigni, Vincenzo, Cairns, Warren, Zavan, Barbara
Format: Article
Language:English
Subjects:
Analysis
Antimicrobial agents
Bacteria
Cytoplasm
Cytotoxicity
Enzymes
Implant dentures
Mitochondria
Molecular weight
Nanocrystals
Nanoparticles
Oxidative stress
Transplants & implants
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Summary:Nanotechnology has gone through a period of rapid growth, thus leading to the constant increase in the application of engineered nanomaterials in daily life. Several different types of nanoparticles have been engineered to be employed in a wide array of applications due to their high surface to volume ratio that leads to unique physical and chemical properties. So far, silver nanoparticles (AgNps) have been used in many more different medical devices than any other nanomaterial, mainly due to their antimicrobial properties. Despite the promising advantages posed by using AgNps in medical applications, the possible health effects associated with the inevitable human exposure to AgNps have raised concerns as to their use since a clear understanding of their specific interaction with biological systems has not been attained yet. In light of such consideration, aim of the present work is the morphological analysis of the intracellular behavior of AgNps with a diameter of 10 nm, with a special attention to their interaction with mitochondria.
ISSN:1687-8728
1687-8736
DOI:10.1155/2013/312747