Lifestyle and Comorbidity-Related Risk Factors of Severe and Critical COVID-19 Infection: A Comparative Study Among Survived COVID-19 Patients in Bangladesh

• Published in: Infection and drug resistance 2021-01, Vol.14, p.4057-4066
• Main Authors: Mohsin, Faroque Md, Nahrin, Ridwana, Tonmon, Tajrin Tahrin, Nesa, Maherun, Tithy, Sharmin Ahmed, Saha, Shuvajit, Mannan, Mahmudul, Shahjalal, Md, Faruque, Mohammad Omar, Hawlader, Mohammad Delwer Hossain
• Format: Article
• Language: English
• Subjects: Age; Alcoholism; Asthma; Asymptomatic; bangladesh; Body weight; comorbidities; Comorbidity; Computer industry; Coronaviruses; COVID-19; Demography; Diabetes; Diabetes mellitus; Disease control; Drug abuse; Health aspects; Hospitals; Hypertension; Infection; Infections; Interviews; Kidney diseases; lifestyle; Lifestyles; Medical research; Medicine, Experimental; Obesity; Original Research; Overweight; Pandemics; Polymerase chain reaction; Questionnaires; Reverse transcription; risk factor; Risk factors; Sleep; Sleep disorders; Smoking; Sociodemographics; Variables
• ISSN: 1178-6973; 1178-6973
• DOI: 10.2147/IDR.S331470

Severe COVID-19 infections have already taken more than 4 million lives worldwide. Factors, such as socio-demographics, comorbidities, lifestyles, environment, and so on, have been widely discussed to be associated with increased severity in many countries. The study aimed to determine the risk factors of severe-critical COVID-19 in Bangladesh. This was a comparative cross-sectional study among various types of COVID-19 patients (both hospitalized and non-hospitalized) confirmed by reverse transcription polymerase chain reaction (RT-PCR). We have selected 1500 COVID-19 positive patients using a convenient sampling technique and analyzed lifestyle and comorbidity-related data using IBM SPSS-23 statistical package software. Chi-square test and multinomial logistic regression were used to determine risk factors of life-threatening COVID-19 infection. The mean age of the study participants was 43.23 (±15.48) years. The study identified several lifestyle-related factors and common commodities as risk factors for severe-critical COVID-19. The patient's age was one of the most important predictors, as people >59 years were at higher risk (AOR=18.223). Among other lifestyle factors, active smoking (AOR=1.482), exposure to secondary smoking (AOR=1.728), sleep disturbance (AOR=2.208) and attachment with SLT/alcohol/substance abuse (AOR=1.804) were identified as significant predictors for severe-critical COVID-19. Patients those were overweight/obese (AOR=2.105), diabetic (AOR=4.286), hypertensive (AOR=3.363), CKD patients (AOR=8.317), asthma patients (AOR=2.152), CVD patients (AOR=7.747) were also at higher risk of severe-critical COVID-19 infection. This study has identified several vital lifestyles and comorbidity-related risk factors of severe-critical COVID-19. People who have these comorbidities should be under high protection, and risky lifestyles of the general population should modify through the proper educational campaign.