A case report and review of the literature: ciprofloxacin resistant Salmonella enterica serovar Typhi in India

Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. An isolate of Salmonella enterica serovar Typhi (S. Typhi...

Full description

Saved in:
Bibliographic Details
Published in:Journal of infection in developing countries 2008-08, Vol.2 (4), p.324-327
Main Authors: Harish, Belgode Narasimha, Menezes, Godfred Antony, Sarangapani, Kengamuthu, Parija, Subhash Chandra
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - therapeutic use
Antibiotics
Case reports
Ciprofloxacin - therapeutic use
drug resistance
Drug Resistance, Multiple, Bacterial
Enteric fever
Humans
India
Male
Microbial Sensitivity Tests
Salmonella
Salmonella Typhi
Salmonella typhi - drug effects
Salmonella typhi - isolation & purification
Typhoid Fever - blood
Typhoid Fever - drug therapy
Typhoid Fever - microbiology
Young Adult
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64 microg/ml. To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxone.
ISSN:2036-6590
1972-2680
1972-2680
DOI:10.3855/jidc.229