Application of Janus Particles in Point-of-Care Testing

Janus particles (JPs), named after the two-faced Roman god, are asymmetric particles with different chemical properties or polarities. JPs have been widely used in the biomedical field in recent years, including as drug carriers for targeted controlled drug release and as biosensors for biological i...

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Bibliographic Details
Published in:Biosensors (Basel) 2022-08, Vol.12 (9), p.689
Main Authors: Wang, Yuhan, Zhao, Peixuan, Zhang, Shihao, Zhu, Kexiao, Shangguan, Xiaoya, Liu, Lishang, Zhang, Shusheng
Format: Article
Language:English
Subjects:
Biomarkers
Biosensors
Chemical properties
detection
Drug carriers
Drug delivery
Health aspects
janus particles
Laboratories
Medical tests
Medical treatment
Methods
Morphology
Nanoparticles
Point of care testing
Polymer blends
Review
Solvents
Technology application
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Summary:Janus particles (JPs), named after the two-faced Roman god, are asymmetric particles with different chemical properties or polarities. JPs have been widely used in the biomedical field in recent years, including as drug carriers for targeted controlled drug release and as biosensors for biological imaging and biomarker detection, which is crucial in the early detection and treatment of diseases. In this review, we highlight the most recent advancements made with regard to Janus particles in point-of-care testing (POCT). Firstly, we introduce several commonly used methods for preparing Janus particles. Secondly, we present biomarker detection using JPs based on various detection methods to achieve the goal of POCT. Finally, we discuss the challenges and opportunities for developing Janus particles in POCT. This review will facilitate the development of POCT biosensing devices based on the unique properties of Janus particles.
ISSN:2079-6374
2079-6374
DOI:10.3390/bios12090689