Clinical and Prognostic Significance of Baseline Serum Vitamin D Levels in Hospitalized Egyptian Covid-19 Patients

Background and Aim: Vitamin D is a hormone with essential roles in both cellular metabolism and immunity. It controls calcium homeostasis and modulates innate and adaptive immune system responses. Many studies suggested an association between vitamin D deficiency and clinical outcomes of covid-19 in...

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Published in:International journal of general medicine 2022-11, Vol.15, p.8063-8070
Main Authors: Mostafa, Sadek, Mohammed, Shaymaa A, Elshennawy, Salwa I, Zakaria, Doaa Mohammed, Mahmoud, Sammar Ahmed Kasim, Alsadek, Amira Mohammed, Ahmad, Inass Hassan, Mohammed, Doaa Sayed, Mohammed, Marwa Abdelmonim, Eltrawy, Heba H
Format: Article
Language:English
Subjects:
Alfacalcidol
Automation
Calcifediol
Coronaviruses
Correlation analysis
COVID-19
Egypt
Ethylenediaminetetraacetic acid
Ferritin
Health aspects
Hospital patients
Hospitalization
Infection
Infections
Laboratories
Metabolism
Mortality
Original Research
Physiological aspects
Regression analysis
Severe acute respiratory syndrome coronavirus 2
Ventilators
Vitamin D
vitamin d deficiency
Vitamin deficiency
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Summary:Background and Aim: Vitamin D is a hormone with essential roles in both cellular metabolism and immunity. It controls calcium homeostasis and modulates innate and adaptive immune system responses. Many studies suggested an association between vitamin D deficiency and clinical outcomes of covid-19 infection, while others failed to document such a relation. The present study aimed to evaluate the clinical and prognostic significance of baseline vitamin D levels in hospitalized Egyptian covid-19 patients. Patients and Methods: The present retrospective study included 300 hospitalized covid-19 patients. Patients were submitted to standard clinical, laboratory, and radiological assessment. According to vitamin D levels, patients were classified to have normal levels ([greater than or equal to]30), insufficient levels (20-29) or deficient levels (
ISSN:1178-7074
1178-7074
DOI:10.2147/IJGM.S386815