Incidence and predictors of heart failure with improved ejection fraction category in a HFrEF patient population

Aims The aim of the study was to assess the incidence and predictive factors of the development of heart failure with improved ejection fraction (HFimpEF) category during a 1 year follow‐up period in a heart failure with reduced ejection fraction (HFrEF) patient population managed in a heart failure...

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Published in:ESC Heart Failure 2024-04, Vol.11 (2), p.783-794
Main Authors: Solymossi, Balázs, Muk, Balázs, Sepp, Róbert, Habon, Tamás, Borbély, Attila, Heltai, Krisztina, Majoros, Zsuzsanna, Járai, Zoltán, Vágány, Dénes, Szatmári, Ákos, Sziliczei, Erzsébet, Bánfi‐Bacsárdi, Fanni, Nyolczas, Noémi
Format: Article
Language:English
Subjects:
Blood pressure
Body mass index
Cardiology
Ejection fraction
Female
Heart Failure
Heart failure with improved ejection fraction
Humans
Incidence
Male
Medical research
Original
Patients
Predictive factors
Prognosis
Research ethics
Reverse remodelling
Risk Factors
Stroke Volume
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Summary:Aims The aim of the study was to assess the incidence and predictive factors of the development of heart failure with improved ejection fraction (HFimpEF) category during a 1 year follow‐up period in a heart failure with reduced ejection fraction (HFrEF) patient population managed in a heart failure outpatient clinic. Methods and results The study evaluated data from patients enrolled in the Hungarian Heart Failure Registry (HHFR). The incidence and predictive factors of the development of the HFimpEF category after 1 year follow‐up were assessed in the group of patients who had HFrEF at baseline. We evaluated the incidence and predictors of the development of HFimpEF after a 1 year follow‐up in relation to time since diagnosis of HFrEF in patients diagnosed within 3 months, between 3 months and 1 year, and beyond 1 year. The predictive factors of the development of HFimpEF were analysed using univariate and multivariate logistic regression analysis. Of the 833 HFrEF patients enrolled in the HHFR, the development of HFimpEF was observed in 162 patients (19.5%) during 1 year follow‐up. In the whole patient population, independent predictors of the development of HFimpEF were female gender [odds ratio (OR): 1.73; 95% confidence interval (CI): 1.01–2.96; P 
ISSN:2055-5822
2055-5822
DOI:10.1002/ehf2.14619