A Viewpoint on the Leaky Gut Syndrome to Treat Allergic Asthma: A Novel Opinion

Asthma is a common respiratory disease characterized by airway inflammation, airway hyperreactivity, and reversible airflow obstruction. Despite current treatments, the prevalence of asthma has increased markedly over decades. According to the theories proposed to explain the pathophysiology of auto...

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Bibliographic Details
Published in:Journal of evidence-based complementary & alternative medicine 2017-07, Vol.22 (3), p.378-380
Main Authors: Farshchi, Masoumeh Kaboli, Azad, Farahzad Jabbari, Salari, Roshanak, Mirsadraee, Majid, Anushiravani, Majid
Format: Article
Language:English
Subjects:
Air flow
Asthma
Asthma - drug therapy
Asthma - etiology
Autoimmune diseases
Brief Communications
Chronic asthma
Chronic illnesses
Chronic respiratory diseases
Disruption
Food intolerance
Gastrointestinal Microbiome
Humans
Inflammation
Integrative medicine
Intestinal Diseases - complications
Intestinal Diseases - drug therapy
Obstruction
Pathophysiology
Permeability
Physicians
Plant Gums - therapeutic use
Plantago
Respiratory diseases
Reversible
Rheumatoid arthritis
Seeds
Small intestine
Tight Junctions - physiology
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Summary:Asthma is a common respiratory disease characterized by airway inflammation, airway hyperreactivity, and reversible airflow obstruction. Despite current treatments, the prevalence of asthma has increased markedly over decades. According to the theories proposed to explain the pathophysiology of autoimmune diseases in integrative medicine, leaky gut syndrome is a phenomenon of increased intestinal permeability due to the disruption of tight junctions and is thought to be related to many chronic diseases, such as food intolerance, inflammatory bowel disease, rheumatoid arthritis, asthma, and other autoimmune disease. One of the classical approaches used by integrative physicians to treat leaky gut syndrome is to repair intestinal permeability to prevent allergic cascade. Due to several mechanisms that have been mentioned in the protective effects of plant gums and plantain family seeds on the intestinal epithelium, we can propose an effective management for leaky gut syndrome to treat asthma.
ISSN:2156-5872
2156-5899
2515-690X
DOI:10.1177/2156587216682169