Financial toxicity in patients with lung cancer: a scoping review protocol

• Published in: BMJ open 2022-05, Vol.12 (5), p.e057801-e057801
• Main Authors: Fu, Liang, Zhuang, Minling, Luo, Chengcan, Zhu, Ruiyun, Wu, Bei, Xu, Wenxia, Xu, Bo, Xu, Ruiyan, Ye, Xianghong
• Format: Article
• Language: English
• Subjects: Adult oncology; Cancer therapies; Cost control; Family income; Financial Stress; Health economics; Humans; Lung cancer; Lung Neoplasms; Mortality; Oncology; Patients; Peer Review; Protocols & guidelines; Research Design; Review Literature as Topic; Systematic Reviews as Topic
• ISSN: 2044-6055; 2044-6055
• DOI: 10.1136/bmjopen-2021-057801

IntroductionLung cancer has the second-ranked morbidity rate and the first-ranked mortality rate worldwide. With the progression of the cancer condition and the advancement of new treatments, the corresponding medical expenses have risen sharply. Nowadays, financial toxicity has become one of the most common concerns in patients with cancer. However, by far, the full landscape of studies on financial toxicity is unclear in patients with lung cancer. Thus, this scoping review aims to summarise the degree, affecting factors, outcomes and intervention strategies of financial toxicity in patients with lung cancer.Methods and analysisThis scoping review will be developed following the methodology described in the Joanna Briggs Institute Manual for Evidence Synthesis on scoping review protocol, which was based on Arksey and O’Malley’s methodological framework, Levac et al’s recommendations for applying this framework and Peters et al’s enhancements of the framework. From the day of database building to 31 December 2021, 10 English databases will be searched in the ‘Abstract’ field with three key search terms: “Lung”, “Cancer” and “Financial toxicity”. The studies’ screening and data extraction will be independently performed by two reviewers (MZ and RZ). Any disagreements between the two reviewers (MZ and RZ) will be resolved by consensus, and a third reviewer (BW) will be invited if necessary. The results will be analysed and presented using tables and figures. This scoping review will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews checklist.Ethics and disseminationAn ethical approval is not required for this scoping review protocol, nor for the scoping review. The results of this scoping review will be disseminated through publication in a peer-reviewed journal or presentation at conferences.RegistrationThis scoping review protocol has been registered in the Open Science Framework (https://osf.io/ub45n/?view_only=bb93eb94e1434a0f8196b3b61cffcec2).