Hyperlipidemia does not influence clinical outcome in arthroscopic treatment of femoroacetabular impingement syndrome

Background Cholesterol can trigger degenerative processes in the chondrocytes. The internal layer of the hip labral consists of cartilage-specific type II collagen-positive fibrocartilage. The purpose of this study was to compare outcomes after arthroscopy labral repair in FAIS patients with preoper...

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Published in:Journal of orthopaedic surgery and research 2022-08, Vol.17 (1), p.1-398, Article 398
Main Authors: Yang, Fan, Huang, Hong-Jie, Zhang, Zhu, Zhang, Xin, Wang, Jian-Quan
Format: Article
Language:English
Subjects:
Activities of daily living
Arthritis
Arthroscopy
Body mass index
Care and treatment
Cartilage
Cholesterol
Chondrocytes
Clinical outcomes
Collagen
Collagen (type II)
Comparative analysis
Diabetes
Femoroacetabular impingement syndrome
Hyperlipidemia
Labrum
Medical research
Medicine, Experimental
Metabolism
Orthopedics
Osteoarthritis
Pain
Patient outcomes
Patient-reported outcomes
Patients
Rehabilitation
Surgery
Surgical outcomes
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Summary:Background Cholesterol can trigger degenerative processes in the chondrocytes. The internal layer of the hip labral consists of cartilage-specific type II collagen-positive fibrocartilage. The purpose of this study was to compare outcomes after arthroscopy labral repair in FAIS patients with preoperative hyperlipidemia to a control group with no hyperlipidemia. Methods Data were prospectively collected and retrospectively reviewed for FAIS patients who had arthroscopy 2019. Patients with hyperlipidemia were 1:1 propensity-score matched to patients without hyperlipidemia. Patient-reported outcomes (HOS-ADL, iHOT-12, mHHS), VAS scores, radiographic measures, performed procedures, complications, and revision surgery were compared and analyzed for both groups. Results A total of 41 patients with hyperlipidemia and 41 patients without hyperlipidemia were found using propensity-score matching. When compared to preoperative levels, both groups demonstrated significant improvements in PROs and VAS scores at the final follow-up. Besides, there were no significant differences in preoperative scores and final outcome scores between the groups. Besides, there were no other differences in revision rate and the rate of meeting the PASS and MCID between the study and the control groups. Conclusion It was demonstrated in this study that FAIS patients with hyperlipidemia can expect to experience similar good short-term patient-reported outcomes as compared with patients without hyperlipidemia. Level of evidence Case-series study; Level of Evidence: Level III. Keywords: Hyperlipidemia, Femoroacetabular impingement syndrome, Patient-reported outcomes
ISSN:1749-799X
1749-799X
DOI:10.1186/s13018-022-03290-3