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Herpes simplex and Ebstein Barr virus encephalitis complicated with Klüver-Bucy syndrome

A case of sixteen-year-old boy with initial herpes simplex virus (HSV) and Epstein-Barr virus (EBV) encephalitis is reported. Herpesviruses are often found in cerebrospinal fluid (CSF) along with EBV. After eradication of HSV in CSF in this case, a positive polymerase chain reaction (PCR) to EBV in...

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Bibliographic Details
Published in:Central European journal of medicine 2013-04, Vol.8 (2), p.213-216
Main Authors: Stojanović, Vesna, Kozić, Duško, Mudrinić, Tatjana Redžek, Doronjski, Aleksandra, Spasojević, Slobodan, Njagulj, Vesna
Format: Article
Language:English
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Summary:A case of sixteen-year-old boy with initial herpes simplex virus (HSV) and Epstein-Barr virus (EBV) encephalitis is reported. Herpesviruses are often found in cerebrospinal fluid (CSF) along with EBV. After eradication of HSV in CSF in this case, a positive polymerase chain reaction (PCR) to EBV in CSF remained along with a severe clinical picture (segmental myoclonus and Klüver-Bucy syndrome) and worsening of brain magnetic resonance imaging (MRI) findings. Neurological and psychological improvement occurred after treatment with intravenous immunoglobulin.
ISSN:1895-1058
2391-5463
1644-3640
2391-5463
DOI:10.2478/s11536-012-0116-7