Antifungal activity of silver nanoparticles obtained by green synthesis

Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The p...

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Bibliographic Details
Published in:Revista do Instituto de Medicina Tropical de São Paulo 2015-03, Vol.57 (2), p.165-167
Main Authors: Mallmann, Eduardo José J, Cunha, Francisco Afrânio, Castro, Bruno N M F, Maciel, Auberson Martins, Menezes, Everardo Albuquerque, Fechine, Pierre Basílio Almeida
Format: Article
Language:English
Subjects:
Antifungal activity
Antifungal Agents - pharmacology
Brief Communications
Candida albicans - drug effects
Candida spp
Candida tropicalis - drug effects
Humans
Metal Nanoparticles
Microbial Sensitivity Tests
Silver - pharmacology
Silver nanoparticles
TROPICAL MEDICINE
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Summary:Silver nanoparticles (AgNPs) are metal structures at the nanoscale. AgNPs have exhibited antimicrobial activities against fungi and bacteria; however synthesis of AgNPs can generate toxic waste during the reaction process. Accordingly, new routes using non-toxic compounds have been researched. The proposal of the present study was to synthesize AgNPs using ribose as a reducing agent and sodium dodecyl sulfate (SDS) as a stabilizer. The antifungal activity of these particles against C. albicans and C. tropicalis was also evaluated. Stable nanoparticles 12.5 ± 4.9 nm (mean ± SD) in size were obtained, which showed high activity against Candida spp. and could represent an alternative for fungal infection treatment.
ISSN:0036-4665
1678-9946
1678-9946
0036-4665
DOI:10.1590/S0036-46652015000200011