Nano-SbCl5/SiO2 as an Efficient Catalyst for One-Pot Synthesis of 2, 4, 5-Trisubstituted Imidazoles Under Solvent- Free Condition

A general synthetic route to the synthesis of imidazoles has been developed using nano SbCl5/SiO2 under solvent-free conditions. The multi-component reactions of aldehydes, benzil and ammonium acetate were carried out to afford some trisubstituted imidazole derivatives. This method provides several...

Full description

Saved in:
Bibliographic Details
Published in:Journal of nanostructures 2012-06, Vol.2 (2), p.221-226
Main Authors: A. Bamoniri, S. Rohani
Format: Article
Language:English
Subjects:
Multi-component reaction
Nano-SbCl5/SiO2
One-pot synthesis
solvent free condition
Trisubstituted Imidazole
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A general synthetic route to the synthesis of imidazoles has been developed using nano SbCl5/SiO2 under solvent-free conditions. The multi-component reactions of aldehydes, benzil and ammonium acetate were carried out to afford some trisubstituted imidazole derivatives. This method provides several advantages like simple work-up, environmentally benign, and shorter reaction times along with high yields. The mentioned nano catalyst was investigated by SEM, TEM and XRD. Meanwhile, structures of trisubstituted imidazoles were elucidated by FT-IR, 1 H NMR and 13 C NMR spectra.
ISSN:2251-7871
2251-788X
DOI:10.7508/jns.2012.02.010