Developmental Programming of Hypertension and Kidney Disease

A growing body of evidence supports the concept that changes in the intrauterine milieu during “sensitive” periods of embryonic development or in infant diet after birth affect the developing individual, resulting in general health alterations later in life. This phenomenon is referred to as “develo...

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Bibliographic Details
Published in:International Journal of Nephrology 2012-01, Vol.2012 (2012), p.603-617
Main Authors: Chong, Euming, Yosypiv, Ihor V.
Format: Article
Language:English
Subjects:
Review
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Summary:A growing body of evidence supports the concept that changes in the intrauterine milieu during “sensitive” periods of embryonic development or in infant diet after birth affect the developing individual, resulting in general health alterations later in life. This phenomenon is referred to as “developmental programming” or “developmental origins of health and disease.” The risk of developing late-onset diseases such as hypertension, chronic kidney disease (CKD), obesity or type 2 diabetes is increased in infants born prematurely at
ISSN:2090-2158
2090-214X
2090-2158
DOI:10.1155/2012/760580