Impact of one-rod levonorgestrel implant on the blood chemistry profile

The aim of this study was to investigate the effect of a one-rod levonorgestrel implant on the blood chemistry profile, including random blood glucose (RBG), haemoglobin (Hb), alanine transferase (ALT), aspartate transferase (AST), and the lipid profile, including total cholesterol, high-density lip...

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Bibliographic Details
Published in:Scientific reports 2021-10, Vol.11 (1), p.20141-20141, Article 20141
Main Authors: Gunardi, Eka R., Surya, Raymond, Syafitri, Inayah, Pasidri, Yogi
Format: Article
Language:English
Subjects:
692/308/2779/109
692/308/2779/777
Adult
Alanine
Blood
Blood Chemical Analysis - methods
Chemistry
Cholesterol
Cholesterol - blood
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Clinical Trials, Phase II as Topic
Contraceptive Agents, Female - administration & dosage
Contraceptive Agents, Female - pharmacology
Drug Implants
Female
Hemoglobin
High density lipoprotein
Humanities and Social Sciences
Humans
Levonorgestrel - administration & dosage
Levonorgestrel - pharmacology
Lipids - blood
Low density lipoprotein
multidisciplinary
Prospective Studies
Science
Science (multidisciplinary)
Transplants & implants
Triglycerides
Triglycerides - blood
Young Adult
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Summary:The aim of this study was to investigate the effect of a one-rod levonorgestrel implant on the blood chemistry profile, including random blood glucose (RBG), haemoglobin (Hb), alanine transferase (ALT), aspartate transferase (AST), and the lipid profile, including total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides. This prospective cohort study was conducted at Raden Saleh Clinic, Jakarta, from 2010 to 2012. The implants were inserted subdermally in 30 patients. The subjects were evaluated every 6 month up to 2 years. Bivariate analysis using t-test or Wilcoxon signed rank test was performed for all variables. p 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-99801-z