Phytosynthesis of silver nanoparticles (AgNPs) using miracle fruit plant (Synsepalum dulcificum) for antimicrobial, catalytic, anticoagulant, and thrombolytic applications

In the present work, we report the phytosynthesis of AgNPs mediated by leaf and seed extracts of . The extracts catalyzed the formation of brown colloidal AgNPs, which stabilized in 10 min. The leaf and seed AgNPs yielded surface plasmon resonance at 440 and 438.5 nm, respectively. Prominent peaks a...

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Bibliographic Details
Published in:Nanotechnology reviews (Berlin) 2016-12, Vol.5 (6), p.507-520
Main Authors: Lateef, Agbaje, Akande, Monsurat A., Azeez, Musibau A., Ojo, Sunday A., Folarin, Bolaji I., Gueguim-Kana, Evariste B., Beukes, Lorika S.
Format: Article
Language:English
Subjects:
Anticoagulants
antimicrobial activity
Catalysis
Catalysts
Colloids
Fourier transforms
Inhibition
Leaves
Nanoparticles
Phenols
phytosynthesis
Seeds
Silver
silver nanoparticles
synsepalum dulcificum
thrombolysis
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Summary:In the present work, we report the phytosynthesis of AgNPs mediated by leaf and seed extracts of . The extracts catalyzed the formation of brown colloidal AgNPs, which stabilized in 10 min. The leaf and seed AgNPs yielded surface plasmon resonance at 440 and 438.5 nm, respectively. Prominent peaks at 3408, 2357, 2089, and 1639 cm were recorded for leaf AgNPs, whereas 3404, 2368, 2081, and 1641 cm were revealed for seed-mediated AgNPs from Fourier transform infrared data. These showed the involvement of phenolic compounds and proteins in the phytosynthesis. The particles were fairly spherical and crystalline in nature having size of 4–26 nm, with prominence of silver in the colloidal solutions. The particles inhibited the growth of drug-resistant strains of and with zone of inhibition of 11–24 mm. Also, the phytosynthesized AgNPs completely inhibited the growth of and . In addition, by using 20 μg/ml of AgNPs, malachite green was degraded by approximately 80% in 24 h. Similarly, the particles displayed blood anticoagulant activities as well as achieved thrombolysis. The AgNPs can be explored for biomedical and catalytic applications. The report is the first on the eco-friendly synthesis of nanoparticles by
ISSN:2191-9089
2191-9097
DOI:10.1515/ntrev-2016-0039