Seaweeds as Source of Bioactive Pigments with Neuroprotective and/or Anti-Neurodegenerative Activities: Astaxanthin and Fucoxanthin

The marine kingdom is an important source of a huge variety of scaffolds inspiring the design of new drugs. The complex molecules found in the oceans present a great challenge to organic and medicinal chemists. However, the wide variety of biological activities they can display is worth the effort....

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Bibliographic Details
Published in:Marine drugs 2024-07, Vol.22 (7), p.327
Main Authors: Guardado Yordi, Estela, Pérez Martínez, Amaury, Radice, Matteo, Scalvenzi, Laura, Abreu-Naranjo, Reinier, Uriarte, Eugenio, Santana, Lourdes, Matos, Maria Joao
Format: Article
Language:English
Subjects:
Algae
Animals
Antioxidants
Astaxanthin
bioactive pigments
Biological activity
Biological effects
Carotenoids
Chlorophyll
Clinical trials
Color
Cyanobacteria
Disease prevention
Displays
Drug development
Food
Fucoxanthin
Functional foods & nutraceuticals
Humans
Marine biology
Marine chemistry
Microorganisms
Neurodegenerative diseases
Neurodegenerative Diseases - drug therapy
Neuroprotection
Neuroprotective Agents - chemistry
Neuroprotective Agents - pharmacology
Oceans
Pharmaceutical industry
Pigments
Pigments, Biological - chemistry
Pigments, Biological - isolation & purification
Pigments, Biological - pharmacology
Plankton
seaweed
Seaweed - chemistry
Seaweeds
Xanthophylls - chemistry
Xanthophylls - isolation & purification
Xanthophylls - pharmacology
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Summary:The marine kingdom is an important source of a huge variety of scaffolds inspiring the design of new drugs. The complex molecules found in the oceans present a great challenge to organic and medicinal chemists. However, the wide variety of biological activities they can display is worth the effort. In this article, we present an overview of different seaweeds as potential sources of bioactive pigments with activity against neurodegenerative diseases, especially due to their neuroprotective effects. Along with a broad introduction to seaweed as a source of bioactive pigments, this review is especially focused on astaxanthin and fucoxanthin as potential neuroprotective and/or anti-neurodegenerative agents. PubMed and SciFinder were used as the main sources to search and select the most relevant scientific articles within the field.
ISSN:1660-3397
1660-3397
DOI:10.3390/md22070327