Detection of Steroids in Topical Fairness Preparations Using Histamine Wheal Test

Topical corticosteroid (TC) abuse is a common, worldwide, problem. One of the recent emerging concerns is the adulteration of TC in fairness cream. The presence of TC in skin-whitening cosmetic creams can be detected by high-performance liquid chromatography (HPLC). Since HPLC is expensive, time-tak...

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Bibliographic Details
Published in:Indian Dermatology Online Journal 2024-05, Vol.15 (3), p.504-506
Main Authors: Nithya, Satish, Srinivas, Chakravarthi R, Lal, Surendranath
Format: Article
Language:English
Subjects:
adulteration
Case Report
fairness creams
histamine wheal test
skin prick test
steroids
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Summary:Topical corticosteroid (TC) abuse is a common, worldwide, problem. One of the recent emerging concerns is the adulteration of TC in fairness cream. The presence of TC in skin-whitening cosmetic creams can be detected by high-performance liquid chromatography (HPLC). Since HPLC is expensive, time-taking and not easily available, we suggest the use of histamine wheal test as a simple and inexpensive test to detect the presence of topical steroids in fairness cream.
ISSN:2229-5178
2249-5673
DOI:10.4103/idoj.idoj_321_23