Elevated Serum Thyroglobulin and Low Iodine Intake Are Associated with Nontoxic Nodular Goiter among Adults Living near the Eastern Mediterranean Coast

Background. Information about iodine intake is crucial for preventing thyroid diseases. Inadequate iodine intake can lead to thyroid diseases, including nontoxic nodular goiter (NNG). Objective. To estimate iodine intake and explore its correlation with thyroid diseases among Israeli adults living n...

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Bibliographic Details
Published in:Journal of Thyroid Research 2014-01, Vol.2014 (2014), p.138-143
Main Authors: Fytlovich, Shlomo, Aharoni, Dorit, Turkot, Svetlana, Gefel, Dov, Ovadia, Yaniv S., Troen, Aron M.
Format: Article
Language:English
Subjects:
Antibodies
Biochemistry
Goiter
Health aspects
Hypothyroidism
Iodine
Nutrition
Questionnaires
Thyroglobulin
Thyroid diseases
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Summary:Background. Information about iodine intake is crucial for preventing thyroid diseases. Inadequate iodine intake can lead to thyroid diseases, including nontoxic nodular goiter (NNG). Objective. To estimate iodine intake and explore its correlation with thyroid diseases among Israeli adults living near the Mediterranean coast, where iodine-depleted desalinated water has become a major source of drinking water. Methods. Cross-sectional study of patients attending Barzilai Medical Center Ashkelon. Participants, who were classified as either NNG (n=17), hypothyroidism (n=14), or control (n=31), provided serum thyroglobulin (Tg) and completed a semiquantitative iodine food frequency questionnaire. Results. Elevated serum Tg values (Tg > 60 ng/mL) were significantly more prevalent in the NNG group than in the other groups (29% versus 7% and 0% for hypothyroidism and controls, resp., P
ISSN:2042-0072
2090-8067
2042-0072
DOI:10.1155/2014/913672