No effects of GSM-modulated 900 MHz electromagnetic fields on survival rate and spontaneous development of lymphoma in female AKR/J mice

Several reports indicated that non-thermal electromagnetic radiation such as from mobile phones and base stations may promote cancer. Therefore, it was investigated experimentally, whether 900 MHz electromagnetic field exposure influences lymphoma development in a mouse strain that is genetically pr...

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Bibliographic Details
Published in:BMC cancer 2004-11, Vol.4 (1), p.77-77, Article 77
Main Authors: Sommer, Angela M, Streckert, Joachim, Bitz, Andreas K, Hansen, Volkert W, Lerchl, Alexander
Format: Article
Language:English
Subjects:
Animals
Body Weight - radiation effects
Cell Phone
Dose-Response Relationship, Radiation
Electromagnetic Fields - adverse effects
Female
Lymphoma - etiology
Mice
Mice, Inbred AKR
Neoplasms, Radiation-Induced - etiology
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Summary:Several reports indicated that non-thermal electromagnetic radiation such as from mobile phones and base stations may promote cancer. Therefore, it was investigated experimentally, whether 900 MHz electromagnetic field exposure influences lymphoma development in a mouse strain that is genetically predisposed to this disease. The AKR/J mice genome carries the AK-virus, which leads within one year to spontaneous development of thymic lymphoblastic lymphoma. 320 unrestrained female mice were sham-exposed or exposed (each n = 160 animals) to GSM like 900 MHz electromagnetic fields for 24 hours per day, 7 days per week, at an average whole body specific absorption rate (SAR) value of 0.4 W/kg. Animals were visually checked daily and were weighed and palpated weekly. Starting with an age of 6 months, blood samples were taken monthly from the tail. Animals with signs of disease or with an age of about 46 weeks were sacrificed and a gross necropsy was performed. Electromagnetic field exposure had a significant effect on body weight gain, with higher values in exposed than in sham-exposed animals. However, survival rate and lymphoma incidence did not differ between exposed and sham-exposed mice. These data do not support the hypothesis that exposure to 900 MHz electromagnetic fields is a significant risk factor for developing lymphoma in a genetically predisposed species, even at a relatively high exposure level.
ISSN:1471-2407
1471-2407
DOI:10.1186/1471-2407-4-77