Point prevalence survey of antimicrobial utilization in a Canadian tertiary-care teaching hospital

Abstract Objectives Inappropriate antimicrobial use can promote antimicrobial resistance, which is associated with increased patient morbidity and mortality. Identifying the pattern of antimicrobial use can provide data from which targeted antimicrobial stewardship interventions can be made. The pri...

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Bibliographic Details
Published in:Journal of epidemiology and global health 2015-06, Vol.5 (2), p.143-150
Main Authors: Lee, Colin, Walker, Sandra A.N, Daneman, Nick, Elligsen, Marion, Palmay, Lesley, Coburn, Bryan, Simor, Andrew
Format: Article
Language:English
Subjects:
Acute care
Antimicrobial agents
Antimicrobial resistance
Infectious diseases
Internal Medicine
Long term health care
Long-term care
Morbidity
Prophylaxis
Prospective
Research Article
Surveillance
Teaching hospitals
Urinary tract
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Summary:Abstract Objectives Inappropriate antimicrobial use can promote antimicrobial resistance, which is associated with increased patient morbidity and mortality. Identifying the pattern of antimicrobial use can provide data from which targeted antimicrobial stewardship interventions can be made. The primary objective was to identify the prevalence of antimicrobial use at a tertiary care teaching hospital with both acute and long-term care patients. Methods A point prevalence study was conducted on July 19th, 2012. Data on antimicrobial utilization, indication for prescribing, duration of therapy, and frequency of infectious disease or antimicrobial stewardship consultations were collected using a customized integrated stewardship database (SPIRIT) and prospective chart review. Results One or more antimicrobial agents were ordered in 31% and 4% of acute care and long-term care patients, respectively. Respiratory and urinary tract infections were the most common indication for antimicrobial therapy in both acute and long-term care. About 25% of surgical prophylaxis orders were prescribed for greater than 24 h. Conclusion This prospective point prevalence survey provided important baseline information on antimicrobial use within a large tertiary care teaching hospital and identified potential targets for future antimicrobial stewardship initiatives. A multi-center point prevalence survey should be considered to identify patterns of antimicrobial use in Canada and to establish the first steps toward international antimicrobial surveillance.
ISSN:2210-6006
2210-6014
2210-6006
DOI:10.1016/j.jegh.2014.06.003