Paediatric Formulation: Design and Development

The development of medicines designed for children can be challenging since this distinct patient population requires specific needs. A formulation designed for paediatric patients must consider the following aspects: patient population variability; dose flexibility; route of administration; patient...

Full description

Saved in:
Bibliographic Details
Published in:International journal of molecular sciences 2020-10, Vol.21 (19), p.7118
Main Authors: Lopalco, Antonio, Denora, Nunzio
Format: Article
Language:English
Subjects:
Age
age-related
Bioavailability
Chemistry, Pharmaceutical
Chemotherapy
Child
children
Design
development
Drug Compounding
Drug delivery
Drug Delivery Systems
Drug Development
Drug dosages
Drug therapy
Excipients
Excipients - chemistry
Excipients - therapeutic use
FDA approval
formulation
Humans
Infant formulas
Leukemia
paediatric
Patients
Pediatrics
Periodicals as Topic
Pharmaceuticals
Physiology
Population
Production processes
Tuberculosis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The development of medicines designed for children can be challenging since this distinct patient population requires specific needs. A formulation designed for paediatric patients must consider the following aspects: patient population variability; dose flexibility; route of administration; patient compliance; drug and excipient tolerability. The purpose of this Special Issue entitled "Paediatric Formulation: Design and Development" is to provide an update on both state-of-the-art methodology and operational challenges in the design and development of paediatric formulations. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients. This editorial, briefly, summarizes the objects of nine original research and review papers published in this Special Issue.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms21197118