Neonatal mortality in the neonatal intensive care unit of Debre Markos referral hospital, Northwest Ethiopia: a prospective cohort study

Neonatal mortality remains a serious global public health problem, but Sub-Saharan Africa (SSA), in particular, is largely affected. Current evidence on neonatal mortality is essential to inform programs and policies, yet there is a scarcity of information concerning neonatal mortality in our study...

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Bibliographic Details
Published in:BMC pediatrics 2020-02, Vol.20 (1), p.72-11, Article 72
Main Authors: Alebel, Animut, Wagnew, Fasil, Petrucka, Pammla, Tesema, Cheru, Moges, Nurilign Abebe, Ketema, Daniel Bekele, Yismaw, Lieltework, Melkamu, Mamaru Wubale, Hibstie, Yitbarek Tenaw, Temesgen, Belisty, Bitew, Zebenay Workneh, Tadesse, Animen Ayehu, Kibret, Getiye Dejenu
Format: Article
Language:English
Subjects:
Age
Apgar score
Birth weight
Births
Breast feeding
Breastfeeding & lactation
Cesarean Section
Cohort analysis
Cohort Studies
Debre Markos referral hospital
Ethiopia - epidemiology
Family physicians
Female
Hospitals
Humans
Infant
Infant Mortality
Infant, Newborn
Intensive care
Intensive Care Units, Neonatal
Low income groups
Male
Medical referrals
Mortality
Mothers
Neonatal care
Neonatal intensive care
Neonatal intensive care unit
Neonatal mortality
Newborn babies
Newborn infants
Northwest Ethiopia
Obstetrics
Patient outcomes
Pregnancy
Prenatal care
Prospective Studies
Public health
Public health movements
Questionnaires
Referral and Consultation
Regression analysis
Respiratory distress syndrome
Retrospective Studies
Risk Factors
Survival analysis
Time
Variables
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Summary:Neonatal mortality remains a serious global public health problem, but Sub-Saharan Africa (SSA), in particular, is largely affected. Current evidence on neonatal mortality is essential to inform programs and policies, yet there is a scarcity of information concerning neonatal mortality in our study area. Therefore, we conducted this prospective cohort study to determine the incidence and predictors of neonatal mortality at Debre Markos Referral Hospital, Northwest Ethiopia. This institutionally-based prospective cohort study was undertaken among 513 neonates admitted to the neonatal intensive care unit of Debre Markos Referral Hospital between December 1st, 2017 and May 30th, 2018. All newborns consecutively admitted to the neonatal intensive care unit during the study period were included. An interviewer administered a questionnaire with the respective mothers. Data were entered using Epi-data™ Version 3.1 and analyzed using STATA™ Version 14. The neonatal survival time was estimated using the Kaplan-Meier survival curve, and the survival time between different categorical variables were compared using the log rank test. Both bi-variable and multivariable Cox-proportional hazard regression models were fitted to identify independent predictors of neonatal mortality. Among a cohort of 513 neonates at Debre Markos Referral Hospital, 109 (21.3%) died during the follow-up time. The overall neonatal mortality rate was 25.8 deaths per 1, 000 neonate-days (95% CI: 21.4, 31.1). In this study, most (83.5%) of the neonatal deaths occurred in the early phase of neonatal period (
ISSN:1471-2431
1471-2431
DOI:10.1186/s12887-020-1963-z