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Baduanjin Mind-Body Exercise for Cancer-Related Fatigue: Protocol for a Remotely Delivered Randomized Wait-List Controlled Feasibility Study

People living with a cancer diagnosis often experience cancer-related fatigue (CRF). Between 9% and 45% of people report CRF as moderate to severe, negatively impacting their quality-of-life (QOL). The evidence-base for managing CRF recommends exercise-related therapies over pharmaceutical intervent...

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Published in:Integrative cancer therapies 2024-01, Vol.23, p.15347354231226127-15347354231226127
Main Authors: Walsh, Sean, Wang, Kang, Lam, Anderson, Du, Shihao, Hu, Yanbin, Sun, Yu-Ting, Tcharkhedian, Elise, Nikas, Evangeline, Webb, Gregory, Moylan, Eugene, Della-Fiorentina, Stephen, Fahey, Paul, Shelley Wang, Xin, Chen, Ming, Zhu, Xiaoshu
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container_title Integrative cancer therapies
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creator Walsh, Sean
Wang, Kang
Lam, Anderson
Du, Shihao
Hu, Yanbin
Sun, Yu-Ting
Tcharkhedian, Elise
Nikas, Evangeline
Webb, Gregory
Moylan, Eugene
Della-Fiorentina, Stephen
Fahey, Paul
Shelley Wang, Xin
Chen, Ming
Zhu, Xiaoshu
description People living with a cancer diagnosis often experience cancer-related fatigue (CRF). Between 9% and 45% of people report CRF as moderate to severe, negatively impacting their quality-of-life (QOL). The evidence-base for managing CRF recommends exercise-related therapies over pharmaceutical interventions. One such exercise-like therapy is Baduanjin mind-body exercise (MBE), which has additional benefits. A remotely delivered program may further benefit people with CRF. The primary objective of this pilot will test study feasibility of a remotely delivered Baduanjin MBE exercise program for people living with CRF. This is a randomized wait-list controlled pilot study and will take place in Sydney, Australia. Subject to informed consent, 40 adults with moderate CRF levels and receiving or previously received adjuvant chemotherapy, will undertake a home-based 8-week Baduanjin MBE program supported by online resources and instructors. The primary feasibility outcomes are recruitment, enrollment, retention, and adherence rates; and safety as measured by tolerance and adverse-event frequency. Clinical outcomes (eg, changes in CRF, QOL, and participant perceptions) are assessed at pre-intervention, week 1, week 4, week 8, and post-intervention. Analyses follows the Intent-to-Treat (all participants as per randomization) and per-protocol (participants adhering to the protocol). Missing data will be imputed from previous data entries and regression models may be tested to predict missing outcomes. To our knowledge, this is the first study evaluating the feasibility and effects of Baduanjin MBE on CRF using a remote delivery method. These feasibility data will inform a fully powered future trial investigating evidence of effect on CRF and QOL. : Australian and New Zealand Clinical Trials Registry (ANZCTR 12623000177651). : 651498 Chinese Medicine Centre.
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Between 9% and 45% of people report CRF as moderate to severe, negatively impacting their quality-of-life (QOL). The evidence-base for managing CRF recommends exercise-related therapies over pharmaceutical interventions. One such exercise-like therapy is Baduanjin mind-body exercise (MBE), which has additional benefits. A remotely delivered program may further benefit people with CRF. The primary objective of this pilot will test study feasibility of a remotely delivered Baduanjin MBE exercise program for people living with CRF. This is a randomized wait-list controlled pilot study and will take place in Sydney, Australia. Subject to informed consent, 40 adults with moderate CRF levels and receiving or previously received adjuvant chemotherapy, will undertake a home-based 8-week Baduanjin MBE program supported by online resources and instructors. 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subjects Adult
Australia
Exercise Therapy - methods
Fatigue - etiology
Fatigue - therapy
Feasibility Studies
Humans
Neoplasms - complications
Quality of Life
Randomized Controlled Trials as Topic
title Baduanjin Mind-Body Exercise for Cancer-Related Fatigue: Protocol for a Remotely Delivered Randomized Wait-List Controlled Feasibility Study
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