Enhanced aerobic exercise performance in women by a combination of three mineral Chelates plus two conditionally essential nutrients

• Published in: Journal of the International Society of Sports Nutrition 2017-11, Vol.14 (1), p.42-42
• Main Authors: DiSilvestro, Robert A, Hart, Staci, Marshall, Trisha, Joseph, Elizabeth, Reau, Alyssa, Swain, Carmen B, Diehl, Jason
• Format: Article
• Language: English
• Subjects: Adult; Aerobics; Anemia; Antioxidants - administration & dosage; Bioavailability; Carnitine; Carnitine - administration & dosage; Chelates; Chelating Agents - administration & dosage; conditionally essential nutrients; Copper; Cytochrome; Dietary minerals; Dietary Supplements; Energy; Enzymes; Exercise; Exercise - physiology; Exercise equipment; Exercise tests; Fatigue; Female; Fitness training programs; Functional foods & nutraceuticals; Healthy Volunteers; Humans; Iron; Metabolism; Metabolites; minerals; Nutrition research; Oxidative stress; Oxygen Consumption - drug effects; Oxygen Consumption - physiology; Phosphatidylserines - administration & dosage; Physical Endurance - drug effects; Physical Endurance - physiology; Physical fitness; Physical Fitness - physiology; Reproducibility of Results; Rodents; running; Sports Nutritional Physiological Phenomena; stationary biking; step test; Young Adult; Young adults; Zinc
• ISSN: 1550-2783; 1550-2783
• DOI: 10.1186/s12970-017-0199-2

Certain essential and conditionally essential nutrients (CENs) perform functions involved in aerobic exercise performance. However, increased intake of such nutrient combinations has not actually been shown to improve such performance. For 1 mo, aerobically fit, young adult women took either a combination of 3 mineral glycinate complexes (daily dose: 36 mg iron, 15 mg zinc, and 2 mg copper) + 2 CENs (daily dose: 2 g carnitine and 400 mg phosphatidylserine), or the same combination with generic mineral complexes, or placebo (  = 14/group). In Trial 1, before and after 1 mo, subjects were tested for 3 mile run time (primary outcome), followed by distance covered in 25 min on a stationary bike (secondary outcome), followed by a 90 s step test (secondary outcome). To test reproducibility of the run results, and to examine a lower dose of carnitine, a second trial was done. New subjects took either mineral glycinates + CENs (1 g carnitine) or placebo (  = 17/group); subjects were tested for pre- and post-treatment 3 mile run time (primary outcome). In Trial 1, the mineral glycinates + CENs decreased 3 mile run time (25.6 ± 2.4 vs 26.5 ± 2.3 min,