Plasma concentrations of ascorbic acid in a cross section of the German population

Objectives Vitamin C deficiency is considered extremely rare in modern industrialized countries. This study was performed to assess vitamin C concentrations in the German population. Methods As part of a consultant–patient seminar on nutrition and food intolerances, patients were asked to participat...

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Bibliographic Details
Published in:Journal of international medical research 2018-01, Vol.46 (1), p.168-174
Main Authors: Hagel, Alexander F., Albrecht, Heinz, Dauth, Wolfgang, Hagel, Wolfgang, Vitali, Francesco, Ganzleben, Ingo, Schultis, Hans W., Konturek, Peter C., Stein, Jürgen, Neurath, Markus F., Raithel, Martin
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
Ascorbic Acid - blood
Ascorbic Acid Deficiency - blood
Ascorbic Acid Deficiency - diagnosis
Ascorbic Acid Deficiency - epidemiology
Body Mass Index
Cross-Sectional Studies
Female
Germany - epidemiology
Humans
Incidence
Male
Middle Aged
Questionnaires
Research Report
Sex Factors
Surveys and Questionnaires
Vitamin C
Vitamin E
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Summary:Objectives Vitamin C deficiency is considered extremely rare in modern industrialized countries. This study was performed to assess vitamin C concentrations in the German population. Methods As part of a consultant–patient seminar on nutrition and food intolerances, patients were asked to participate in this study on a voluntary basis. Blood samples were taken for analysis of serum vitamin C concentrations, and all patients were asked to complete a questionnaire. The vitamin C concentration was determined by high-performance liquid chromatography. Results Of approximately 300 patients attending the seminar, 188 (62.6%) consented to vitamin C blood sample analysis and 178 (59.3%) answered the questionnaire. The mean vitamin C concentration was 7.98 mg/L (range, 0.50–17.40; reference range, 5–15 mg/L). A low plasma level with vitamin C insufficiency (
ISSN:0300-0605
1473-2300
DOI:10.1177/0300060517714387