Clinicopathological features and surgical procedures of adnexal masses with abdominal pain in pediatric and adolescent patients

• Published in: Orphanet journal of rare diseases 2024-03, Vol.19 (1), p.132-132, Article 132
• Main Authors: Liu, Qian, Li, Zhiqiang, Zhou, Huimei, Cao, Dongyan, Yang, Jiaxin, Shen, Keng, Lang, Jinghe
• Format: Article
• Language: English
• Subjects: Abdomen; Abdominal pain; Adnexitis; Adolescent; Appendicitis; Biomarkers; Care and treatment; Causes of; Chemotherapy; Cysts; Demographic aspects; Development and progression; Diagnosis; Ectopic pregnancy; Fertility; Laparoscopy; Laparotomy; Magnetic resonance imaging; Management science; Medical records; Medical research; Medicine, Experimental; Menstruation; Nausea; Ovarian mass; Ovaries; Pain; Pathology; Patients; Pediatric; Pediatrics; Pregnancy complications; Regression analysis; Steroids; Surgery; Teenagers; Teratoma; Tomography; Tumor markers; Tumors; Ultrasonic imaging; Vomiting
• ISSN: 1750-1172; 1750-1172
• DOI: 10.1186/s13023-024-03101-4

This study investigated the clinicopathological features and surgical procedures of adnexal masses with abdominal pain in pediatric and adolescent patients. Our objective was to better define the clinical presentation of adnexal torsion and to distinguish characteristics of those with torsion and those with an alternate diagnosis. Retrospective cohort study of 212 pediatric and adolescent patients was performed who admitted for abdominal pain and presenting with an adnexal mass between March 2012 to December 2019.Medical records were reviewed for age at operation, including presentation of symptoms and signs; the levels of tumor markers; imaging examinations; pathologic findings; the size of masses; treatment; and outcome. Data management and descriptive analyses were performed using SPSS 26.0. The median age of the patients was 14.5 ± 3.6 years at the operation. 126 (59.4%, 126/212) patients presented with an abrupt onset of abdominal pain. A total of 82.1% (174/212) of the participants underwent adnexal conservative surgery. 179 (84.5%, 179/212) patients underwent laparoscopic surgery with an average tumor size of 7.7 ± 3.4 cm, while 33 patients ( 15.6%, 33/212) underwent laparotomy. Rupture of mass and ectopic pregnancy accounted for 7.5% (16/212) and 0.9%(2/212), respectively. Torsion was responsible for 36.8% (78/212) of all patients. Among the patients with torsion, the symptom of nausea and vomiting was more common among girls without torsion (P