Prognostic assessment of relative apical sparing pattern of longitudinal strain for severe aortic valve stenosis

The relative apical sparing pattern (RASP) of left ventricular (LV) longitudinal strain (LS) is frequently associated with cardiac amyloidosis. Elderly patients with aortic valve stenosis (AS) complicated by transthyretin amyloid cardiomyopathy have poor prognosis. Furthermore, deteriorated basal LS...

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Bibliographic Details
Published in:International journal of cardiology. Heart & vasculature 2020-08, Vol.29, p.100551-100551, Article 100551
Main Authors: Saito, Makoto, Imai, Misaki, Wake, Daisuke, Higaki, Rieko, Nakao, Yasuhisa, Morioka, Hiroe, Sumimoto, Takumi, Inoue, Katsuji
Format: Article
Language:English
Subjects:
Adverse cardiac events
Aortic valve stenosis
Apical sparing
Cardiac amyloidosis
Longitudinal strain
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Summary:The relative apical sparing pattern (RASP) of left ventricular (LV) longitudinal strain (LS) is frequently associated with cardiac amyloidosis. Elderly patients with aortic valve stenosis (AS) complicated by transthyretin amyloid cardiomyopathy have poor prognosis. Furthermore, deteriorated basal LS in AS patients has been reported to be associated with adverse outcome. We investigated the association between RASP and outcomes in patients with severe AS. We retrospectively studied 156 consecutive patients with severe AS and preserved LV ejection fraction. RASP was assessed by both of semi-quantitative (sRASP) and quantitative (qRASP) methods. sRASP was defined as a deterioration of LS (≥-10%) in ≥ 5 (of 6) basal segments, relative to preserved LS (
ISSN:2352-9067
2352-9067
DOI:10.1016/j.ijcha.2020.100551