Comparison of Estimated LDL Cholesterol Equations with Direct Measurement in Patients with Angiographically Confirmed Coronary Artery Disease

Background and aims: Our goals in the study were to (1) quantify the discordance in LDL-C levels between equations (the Friedewald, Sampson, and Martin/Hopkins equations) and compare them with direct LDL-C (dLDL-C); and (2) explore the proportion of misclassified patients by calculated LDL-C using t...

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Published in:Journal of cardiovascular development and disease 2022-10, Vol.9 (10), p.342
Main Authors: Shi, Boqun, Wang, Hao-Yu, Yin, Dong, Zhu, Chenggang, Feng, Lei, Wang, Hongjian, Jia, Lei, Fu, Rui, Song, Chenxi, Zhou, Zhou, Lin, Yahui, Song, Weihua, Dou, Ke-Fei
Format: Article
Language:English
Subjects:
Cardiology
Cardiovascular disease
Cholesterol
Coronary vessels
Diabetes
High density lipoprotein
LDL-C
Lipids
Lipoproteins
Methods
Population
Values
Variables
Vein & artery diseases
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Summary:Background and aims: Our goals in the study were to (1) quantify the discordance in LDL-C levels between equations (the Friedewald, Sampson, and Martin/Hopkins equations) and compare them with direct LDL-C (dLDL-C); and (2) explore the proportion of misclassified patients by calculated LDL-C using these three different equations. Methods: A total of 30,349 consecutive patients with angiographically confirmed coronary artery disease (CAD) were prospectively enrolled. Concordance was defined as if the LDL-C was
ISSN:2308-3425
2308-3425
DOI:10.3390/jcdd9100342