Hepatoid adenocarcinoma of the gallbladder

Hepatoid adenocarcinoma is a rare variant of extrahepatic adenocarcinoma which behaves like hepatocellular carcinoma in morphology and functionality. We present a rare case of hepatoid adenocarcinoma of the gallbladder which invades deeply the liver bed, in a 59-year-old woman. Histologically, most...

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Bibliographic Details
Published in:World journal of surgical oncology 2011-09, Vol.9 (1), p.103-103, Article 103
Main Authors: Ellouze, Sameh, Slim, Charfi, Ahmad, Guirat, Naourez, Gouiaa, Ali, Amouri, Héla, Mnif, Mariem, Kossentini, Mohamed, Ben Amar, Tahia, Boudawara
Format: Article
Language:English
Subjects:
adenocarcinoma
Adenocarcinoma - diagnosis
Adenocarcinoma - surgery
Biopsy
Cancer
Case Report
Cytoplasm
Diagnosis, Differential
Female
gallbladder
Gallbladder Neoplasms - diagnosis
Gallbladder Neoplasms - surgery
Hepatectomy
hepathocellular carcinoma
Hepatitis
Hepatoid
histopathology
Humans
liver
Liver cancer
Middle Aged
Surgery
Tomography
Tomography, X-Ray Computed
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Summary:Hepatoid adenocarcinoma is a rare variant of extrahepatic adenocarcinoma which behaves like hepatocellular carcinoma in morphology and functionality. We present a rare case of hepatoid adenocarcinoma of the gallbladder which invades deeply the liver bed, in a 59-year-old woman. Histologically, most of the mass in the gallbladder was composed of cells with eosinophilic cytoplasm arranged in a trabecular pattern, which resembled hepatocellular carcinoma. The main differential diagnosis was hepatocellular carcinoma with invasion into the gallbladder. The gallbladder origin of the hepatoid adenocarcinoma was verified by the presence of foci of conventional adenocarcinoma, the recognition of high-grade dysplasia in the adjacent epithelium and the absence of cirrhosis.
ISSN:1477-7819
1477-7819
DOI:10.1186/1477-7819-9-103