Optical coherence tomography of the preterm eye: from retinopathy of prematurity to brain development

Preterm infants with retinopathy of prematurity are at increased risk of poor neurodevelopmental outcomes. Because the neurosensory retina is an extension of the central nervous system, anatomic abnormalities in the anterior visual pathway often relate to system and central nervous system health. We...

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Bibliographic Details
Published in:Eye and brain 2016-01, Vol.8 (Issue 1), p.123-133
Main Authors: Rothman, Adam L, Mangalesh, Shwetha, Chen, Xi, Toth, Cynthia A
Format: Article
Language:English
Subjects:
Babies
brain
Brain research
Dietary fiber
eye
Eye diseases
infant
Medical imaging
neurodevelopment
Newborn babies
NMR
Nuclear magnetic resonance
Optic nerve
optical coherence tomography
Optics
Pediatrics
Premature birth
Retina
retinopathy of prematurity
Review
Telemedicine
Tomography
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Summary:Preterm infants with retinopathy of prematurity are at increased risk of poor neurodevelopmental outcomes. Because the neurosensory retina is an extension of the central nervous system, anatomic abnormalities in the anterior visual pathway often relate to system and central nervous system health. We describe optical coherence tomography as a powerful imaging modality that has recently been adapted to the infant population and provides noninvasive, high-resolution, cross-sectional imaging of the infant eye at the bedside. Optical coherence tomography has increased understanding of normal eye development and has identified several potential biomarkers of brain abnormalities and poorer neurodevelopment.
ISSN:1179-2744
1179-2744
DOI:10.2147/EB.S97660