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Vertebral bone quality score was associated with paraspinal muscles fat infiltration, but not modic classification in patients with chronic low back pain: a prospective cross-sectional study
The lumbar vertebra and paraspinal muscles play an important role in maintaining the stability of the lumbar spine. Therefore, the aim of this study was to investigate the relationship between paraspinal muscles fat infiltration and vertebral body related changes [vertebral bone quality (VBQ) score...
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| Published in: | BMC musculoskeletal disorders 2024-07, Vol.25 (1), p.509-8, Article 509 |
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| creator | Chen, Jiaxin Huang, Yilong Yang, Yingjuan Wang, Zhongwei Zhao, Derong Luo, Mingbin Pu, Fushun Yang, Juntao Zhang, Zhenguang He, Bo |
| description | The lumbar vertebra and paraspinal muscles play an important role in maintaining the stability of the lumbar spine. Therefore, the aim of this study was to investigate the relationship between paraspinal muscles fat infiltration and vertebral body related changes [vertebral bone quality (VBQ) score and Modic changes (MCs)] in patients with chronic low back pain (CLBP).
Patients with CLBP were prospectively collected in four hospitals and all patients underwent 3.0T magnetic resonance scanning. Basic clinical information was collected, including age, sex, course of disease (COD), and body mass index (BMI). MCs were divided into 3 types based on their signal intensity on T1 and T2-weighted imaging. VBQ was obtained by midsagittal T1-weighted imaging (T1WI) and calculated using the formula: SI
/SI
. The Proton density fat fraction (PDFF) values and cross-sectional area (CSA) of paraspinal muscles were measured on the fat fraction map from the iterative decomposition of water and fat with the echo asymmetry and least-squares estimation quantitation (IDEAL-IQ) sequences and in/out phase images at the central level of the L4/5 and L5/S1 discs.
This study included 476 patients with CLBP, including 189 males and 287 females. 69% had no Modic changes and 31% had Modic changes. There was no difference in CSA and PDFF for multifidus(MF) and erector spinae (ES) at both levels between Modic type I and type II, all P values>0.05. Spearman correlation analysis showed that VBQ was weakly negatively correlated with paraspinal muscles CSA (all r values |
| doi_str_mv | 10.1186/s12891-024-07626-4 |
| format | article |
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Patients with CLBP were prospectively collected in four hospitals and all patients underwent 3.0T magnetic resonance scanning. Basic clinical information was collected, including age, sex, course of disease (COD), and body mass index (BMI). MCs were divided into 3 types based on their signal intensity on T1 and T2-weighted imaging. VBQ was obtained by midsagittal T1-weighted imaging (T1WI) and calculated using the formula: SI
/SI
. The Proton density fat fraction (PDFF) values and cross-sectional area (CSA) of paraspinal muscles were measured on the fat fraction map from the iterative decomposition of water and fat with the echo asymmetry and least-squares estimation quantitation (IDEAL-IQ) sequences and in/out phase images at the central level of the L4/5 and L5/S1 discs.
This study included 476 patients with CLBP, including 189 males and 287 females. 69% had no Modic changes and 31% had Modic changes. There was no difference in CSA and PDFF for multifidus(MF) and erector spinae (ES) at both levels between Modic type I and type II, all P values>0.05. Spearman correlation analysis showed that VBQ was weakly negatively correlated with paraspinal muscles CSA (all r values < 0.3 and all p values < 0.05), moderately positive correlation with PDFF of MF at L4/5 level (r values = 0.304, p values<0.001) and weakly positively correlated with PDFF of other muscles (all r values<0.3 and all p values<0.001). Multivariate linear regression analysis showed that age (β = 0.141, p < 0.001), gender (β = 4.285, p < 0.001) and VBQ (β = 1.310, p = 0.001) were related to the total PDFF of muscles. For MCs, binary logistic regression showed that the odds ratio values of age, BMI and COD were 1.092, 1.082 and 1.004, respectively (all p values ＜ 0.05).
PDFF of paraspinal muscles was not associated with Modic classification. In addition to age and gender, PDFF of paraspinal muscles is also affected by VBQ. Age and BMI are considered risk factors for the MCs in CLBP patients.]]></description><identifier>ISSN: 1471-2474</identifier><identifier>EISSN: 1471-2474</identifier><identifier>DOI: 10.1186/s12891-024-07626-4</identifier><identifier>PMID: 38956545</identifier><language>eng</language><publisher>England: BioMed Central Ltd</publisher><subject>Abdomen ; Adipose Tissue - diagnostic imaging ; Adipose Tissue - pathology ; Adult ; Age ; Aged ; Back pain ; Backache ; Body mass index ; Bodybuilders ; Bone density ; Bone marrow ; Chronic illnesses ; Chronic low back pain ; Chronic pain ; Chronic Pain - diagnostic imaging ; Classification ; Correlation analysis ; Cross-Sectional Studies ; Development and progression ; Fat infiltration ; Female ; Gender ; Health facilities ; Humans ; Low back pain ; Low Back Pain - diagnostic imaging ; Lumbar Vertebrae - diagnostic imaging ; Lumbar Vertebrae - pathology ; Magnetic Resonance Imaging ; Male ; Medical research ; Medicine, Experimental ; Middle Aged ; Modic changes ; Muscles ; Neuromuscular diseases ; Normal distribution ; Paraspinal muscles ; Paraspinal Muscles - diagnostic imaging ; Paraspinal Muscles - pathology ; Patients ; Physiological aspects ; Prospective Studies ; Regression analysis ; Reproducibility ; Risk factors ; Spine (lumbar) ; Statistical analysis ; Tomography ; Vertebrae ; Vertebral bone quality score</subject><ispartof>BMC musculoskeletal disorders, 2024-07, Vol.25 (1), p.509-8, Article 509</ispartof><rights>2024. The Author(s).</rights><rights>COPYRIGHT 2024 BioMed Central Ltd.</rights><rights>2024. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c401t-cd2c7f39a7676eceeee663b0169fcbc7bce64f098d130b3c04658cb63d6b068c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11221129/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3079213067?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25744,27915,27916,37003,37004,38507,43886,44581,53782,53784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38956545$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Jiaxin</creatorcontrib><creatorcontrib>Huang, Yilong</creatorcontrib><creatorcontrib>Yang, Yingjuan</creatorcontrib><creatorcontrib>Wang, Zhongwei</creatorcontrib><creatorcontrib>Zhao, Derong</creatorcontrib><creatorcontrib>Luo, Mingbin</creatorcontrib><creatorcontrib>Pu, Fushun</creatorcontrib><creatorcontrib>Yang, Juntao</creatorcontrib><creatorcontrib>Zhang, Zhenguang</creatorcontrib><creatorcontrib>He, Bo</creatorcontrib><title>Vertebral bone quality score was associated with paraspinal muscles fat infiltration, but not modic classification in patients with chronic low back pain: a prospective cross-sectional study</title><title>BMC musculoskeletal disorders</title><addtitle>BMC Musculoskelet Disord</addtitle><description><![CDATA[The lumbar vertebra and paraspinal muscles play an important role in maintaining the stability of the lumbar spine. Therefore, the aim of this study was to investigate the relationship between paraspinal muscles fat infiltration and vertebral body related changes [vertebral bone quality (VBQ) score and Modic changes (MCs)] in patients with chronic low back pain (CLBP).
Patients with CLBP were prospectively collected in four hospitals and all patients underwent 3.0T magnetic resonance scanning. Basic clinical information was collected, including age, sex, course of disease (COD), and body mass index (BMI). MCs were divided into 3 types based on their signal intensity on T1 and T2-weighted imaging. VBQ was obtained by midsagittal T1-weighted imaging (T1WI) and calculated using the formula: SI
/SI
. The Proton density fat fraction (PDFF) values and cross-sectional area (CSA) of paraspinal muscles were measured on the fat fraction map from the iterative decomposition of water and fat with the echo asymmetry and least-squares estimation quantitation (IDEAL-IQ) sequences and in/out phase images at the central level of the L4/5 and L5/S1 discs.
This study included 476 patients with CLBP, including 189 males and 287 females. 69% had no Modic changes and 31% had Modic changes. There was no difference in CSA and PDFF for multifidus(MF) and erector spinae (ES) at both levels between Modic type I and type II, all P values>0.05. Spearman correlation analysis showed that VBQ was weakly negatively correlated with paraspinal muscles CSA (all r values < 0.3 and all p values < 0.05), moderately positive correlation with PDFF of MF at L4/5 level (r values = 0.304, p values<0.001) and weakly positively correlated with PDFF of other muscles (all r values<0.3 and all p values<0.001). Multivariate linear regression analysis showed that age (β = 0.141, p < 0.001), gender (β = 4.285, p < 0.001) and VBQ (β = 1.310, p = 0.001) were related to the total PDFF of muscles. For MCs, binary logistic regression showed that the odds ratio values of age, BMI and COD were 1.092, 1.082 and 1.004, respectively (all p values ＜ 0.05).
PDFF of paraspinal muscles was not associated with Modic classification. In addition to age and gender, PDFF of paraspinal muscles is also affected by VBQ. Age and BMI are considered risk factors for the MCs in CLBP patients.]]></description><subject>Abdomen</subject><subject>Adipose Tissue - diagnostic imaging</subject><subject>Adipose Tissue - pathology</subject><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Back pain</subject><subject>Backache</subject><subject>Body mass index</subject><subject>Bodybuilders</subject><subject>Bone density</subject><subject>Bone marrow</subject><subject>Chronic illnesses</subject><subject>Chronic low back pain</subject><subject>Chronic pain</subject><subject>Chronic Pain - diagnostic imaging</subject><subject>Classification</subject><subject>Correlation analysis</subject><subject>Cross-Sectional Studies</subject><subject>Development and progression</subject><subject>Fat infiltration</subject><subject>Female</subject><subject>Gender</subject><subject>Health facilities</subject><subject>Humans</subject><subject>Low back pain</subject><subject>Low Back Pain - diagnostic imaging</subject><subject>Lumbar Vertebrae - diagnostic imaging</subject><subject>Lumbar Vertebrae - pathology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical research</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Modic changes</subject><subject>Muscles</subject><subject>Neuromuscular diseases</subject><subject>Normal distribution</subject><subject>Paraspinal muscles</subject><subject>Paraspinal Muscles - diagnostic imaging</subject><subject>Paraspinal Muscles - pathology</subject><subject>Patients</subject><subject>Physiological aspects</subject><subject>Prospective Studies</subject><subject>Regression analysis</subject><subject>Reproducibility</subject><subject>Risk factors</subject><subject>Spine (lumbar)</subject><subject>Statistical analysis</subject><subject>Tomography</subject><subject>Vertebrae</subject><subject>Vertebral bone quality score</subject><issn>1471-2474</issn><issn>1471-2474</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>COVID</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptUk1v1DAUjBCIlsIf4IAsceFAih0ntsMFVRUflSpxAa6W_eLseknire10tX-O38bb3VK6iERRbL-ZeXrjKYqXjJ4zpsS7xCrVspJWdUmlqERZPypOWS1ZWdWyfvxgfVI8S2lFKZOKt0-LE67aRjR1c1r8-uFidjaagdgwOXIzm8HnLUkQoiMbk4hJKYA32XVk4_OSrE00ae0nZIxzgsEl0ptM_NT7IUeTfZjeEjtnMoVMxtB5IDCgiO897KsIRZHs3ZTTQRKWMUyIG8KGWAM_seyn98SQdQxp7SD7W0cA16lMu13YNU957rbPiye9GZJ7cfc_K75_-vjt8kt5_fXz1eXFdQk1ZbmErgLZ89ZIIYUDh48Q3FIm2h4sSAtO1D1tVcc4tRxoLRoFVvBOWCoU8LPi6qDbBbPS6-hHE7c6GK_3ByEutInZoxsaOdyBxE4Gascr1cuGd0rZRpq-7xxqfThorWc7ug7QB7T_SPS4MvmlXoRbzVhV4deiwps7hRhuZpeyHn0CNwxmcmFOmlNsKYWqKEJf_wNdhTmif3tUW-G8Qv5FLQxOgFcZsDHsRPWFbFvVKkk5os7_g8K3c6MHTA8mwB0TqgNhf3fR9fdDMqp3EdaHCGuMsN5HWNdIevXQnnvKn8zy32Uy8Zw</recordid><startdate>20240703</startdate><enddate>20240703</enddate><creator>Chen, Jiaxin</creator><creator>Huang, Yilong</creator><creator>Yang, Yingjuan</creator><creator>Wang, Zhongwei</creator><creator>Zhao, Derong</creator><creator>Luo, Mingbin</creator><creator>Pu, Fushun</creator><creator>Yang, Juntao</creator><creator>Zhang, Zhenguang</creator><creator>He, Bo</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TK</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>COVID</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20240703</creationdate><title>Vertebral bone quality score was associated with paraspinal muscles fat infiltration, but not modic classification in patients with chronic low back pain: a prospective cross-sectional study</title><author>Chen, Jiaxin ; Huang, Yilong ; Yang, Yingjuan ; Wang, Zhongwei ; Zhao, Derong ; Luo, Mingbin ; Pu, Fushun ; Yang, Juntao ; Zhang, Zhenguang ; He, Bo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c401t-cd2c7f39a7676eceeee663b0169fcbc7bce64f098d130b3c04658cb63d6b068c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abdomen</topic><topic>Adipose Tissue - diagnostic imaging</topic><topic>Adipose Tissue - pathology</topic><topic>Adult</topic><topic>Age</topic><topic>Aged</topic><topic>Back pain</topic><topic>Backache</topic><topic>Body mass index</topic><topic>Bodybuilders</topic><topic>Bone density</topic><topic>Bone marrow</topic><topic>Chronic illnesses</topic><topic>Chronic low back pain</topic><topic>Chronic pain</topic><topic>Chronic Pain - diagnostic imaging</topic><topic>Classification</topic><topic>Correlation analysis</topic><topic>Cross-Sectional Studies</topic><topic>Development and progression</topic><topic>Fat infiltration</topic><topic>Female</topic><topic>Gender</topic><topic>Health facilities</topic><topic>Humans</topic><topic>Low back pain</topic><topic>Low Back Pain - diagnostic imaging</topic><topic>Lumbar Vertebrae - diagnostic imaging</topic><topic>Lumbar Vertebrae - pathology</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medical research</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Modic changes</topic><topic>Muscles</topic><topic>Neuromuscular diseases</topic><topic>Normal distribution</topic><topic>Paraspinal muscles</topic><topic>Paraspinal Muscles - diagnostic imaging</topic><topic>Paraspinal Muscles - pathology</topic><topic>Patients</topic><topic>Physiological aspects</topic><topic>Prospective Studies</topic><topic>Regression analysis</topic><topic>Reproducibility</topic><topic>Risk factors</topic><topic>Spine (lumbar)</topic><topic>Statistical analysis</topic><topic>Tomography</topic><topic>Vertebrae</topic><topic>Vertebral bone quality score</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Jiaxin</creatorcontrib><creatorcontrib>Huang, Yilong</creatorcontrib><creatorcontrib>Yang, Yingjuan</creatorcontrib><creatorcontrib>Wang, Zhongwei</creatorcontrib><creatorcontrib>Zhao, Derong</creatorcontrib><creatorcontrib>Luo, Mingbin</creatorcontrib><creatorcontrib>Pu, Fushun</creatorcontrib><creatorcontrib>Yang, Juntao</creatorcontrib><creatorcontrib>Zhang, Zhenguang</creatorcontrib><creatorcontrib>He, Bo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Coronavirus Research Database</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Publicly Available Content (ProQuest)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>BMC musculoskeletal disorders</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Jiaxin</au><au>Huang, Yilong</au><au>Yang, Yingjuan</au><au>Wang, Zhongwei</au><au>Zhao, Derong</au><au>Luo, Mingbin</au><au>Pu, Fushun</au><au>Yang, Juntao</au><au>Zhang, Zhenguang</au><au>He, Bo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vertebral bone quality score was associated with paraspinal muscles fat infiltration, but not modic classification in patients with chronic low back pain: a prospective cross-sectional study</atitle><jtitle>BMC musculoskeletal disorders</jtitle><addtitle>BMC Musculoskelet Disord</addtitle><date>2024-07-03</date><risdate>2024</risdate><volume>25</volume><issue>1</issue><spage>509</spage><epage>8</epage><pages>509-8</pages><artnum>509</artnum><issn>1471-2474</issn><eissn>1471-2474</eissn><abstract><![CDATA[The lumbar vertebra and paraspinal muscles play an important role in maintaining the stability of the lumbar spine. Therefore, the aim of this study was to investigate the relationship between paraspinal muscles fat infiltration and vertebral body related changes [vertebral bone quality (VBQ) score and Modic changes (MCs)] in patients with chronic low back pain (CLBP).
Patients with CLBP were prospectively collected in four hospitals and all patients underwent 3.0T magnetic resonance scanning. Basic clinical information was collected, including age, sex, course of disease (COD), and body mass index (BMI). MCs were divided into 3 types based on their signal intensity on T1 and T2-weighted imaging. VBQ was obtained by midsagittal T1-weighted imaging (T1WI) and calculated using the formula: SI
/SI
. The Proton density fat fraction (PDFF) values and cross-sectional area (CSA) of paraspinal muscles were measured on the fat fraction map from the iterative decomposition of water and fat with the echo asymmetry and least-squares estimation quantitation (IDEAL-IQ) sequences and in/out phase images at the central level of the L4/5 and L5/S1 discs.
This study included 476 patients with CLBP, including 189 males and 287 females. 69% had no Modic changes and 31% had Modic changes. There was no difference in CSA and PDFF for multifidus(MF) and erector spinae (ES) at both levels between Modic type I and type II, all P values>0.05. Spearman correlation analysis showed that VBQ was weakly negatively correlated with paraspinal muscles CSA (all r values < 0.3 and all p values < 0.05), moderately positive correlation with PDFF of MF at L4/5 level (r values = 0.304, p values<0.001) and weakly positively correlated with PDFF of other muscles (all r values<0.3 and all p values<0.001). Multivariate linear regression analysis showed that age (β = 0.141, p < 0.001), gender (β = 4.285, p < 0.001) and VBQ (β = 1.310, p = 0.001) were related to the total PDFF of muscles. For MCs, binary logistic regression showed that the odds ratio values of age, BMI and COD were 1.092, 1.082 and 1.004, respectively (all p values ＜ 0.05).
PDFF of paraspinal muscles was not associated with Modic classification. In addition to age and gender, PDFF of paraspinal muscles is also affected by VBQ. Age and BMI are considered risk factors for the MCs in CLBP patients.]]></abstract><cop>England</cop><pub>BioMed Central Ltd</pub><pmid>38956545</pmid><doi>10.1186/s12891-024-07626-4</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1471-2474 |
| ispartof | BMC musculoskeletal disorders, 2024-07, Vol.25 (1), p.509-8, Article 509 |
| issn | 1471-2474 1471-2474 |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_3d63ec7767ac4e328f753d88b57affde |
| source | Open Access: PubMed Central; Publicly Available Content (ProQuest); Coronavirus Research Database |
| subjects | Abdomen Adipose Tissue - diagnostic imaging Adipose Tissue - pathology Adult Age Aged Back pain Backache Body mass index Bodybuilders Bone density Bone marrow Chronic illnesses Chronic low back pain Chronic pain Chronic Pain - diagnostic imaging Classification Correlation analysis Cross-Sectional Studies Development and progression Fat infiltration Female Gender Health facilities Humans Low back pain Low Back Pain - diagnostic imaging Lumbar Vertebrae - diagnostic imaging Lumbar Vertebrae - pathology Magnetic Resonance Imaging Male Medical research Medicine, Experimental Middle Aged Modic changes Muscles Neuromuscular diseases Normal distribution Paraspinal muscles Paraspinal Muscles - diagnostic imaging Paraspinal Muscles - pathology Patients Physiological aspects Prospective Studies Regression analysis Reproducibility Risk factors Spine (lumbar) Statistical analysis Tomography Vertebrae Vertebral bone quality score |
| title | Vertebral bone quality score was associated with paraspinal muscles fat infiltration, but not modic classification in patients with chronic low back pain: a prospective cross-sectional study |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T23%3A37%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Vertebral%20bone%20quality%20score%20was%20associated%20with%20paraspinal%20muscles%20fat%20infiltration,%20but%20not%20modic%20classification%20in%20patients%20with%20chronic%20low%20back%20pain:%20a%20prospective%20cross-sectional%20study&rft.jtitle=BMC%20musculoskeletal%20disorders&rft.au=Chen,%20Jiaxin&rft.date=2024-07-03&rft.volume=25&rft.issue=1&rft.spage=509&rft.epage=8&rft.pages=509-8&rft.artnum=509&rft.issn=1471-2474&rft.eissn=1471-2474&rft_id=info:doi/10.1186/s12891-024-07626-4&rft_dat=%3Cgale_doaj_%3EA799898703%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c401t-cd2c7f39a7676eceeee663b0169fcbc7bce64f098d130b3c04658cb63d6b068c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3079213067&rft_id=info:pmid/38956545&rft_galeid=A799898703&rfr_iscdi=true |