Incidence and factors associated with genitourinary infections among Type 2 diabetes patients on SGLT2 Inhibitors: A single retrospective cohort study

•Genitourinary infections are quite common among diabetic patients, and some studies suggest that the use of SGLT2 inhibitors further increases this potential risk•The 3 and 6 month incidence of genitourinary infections among type 2 diabetics is higher with dapagliflozin and empagliflozin.•Factors a...

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Bibliographic Details
Published in:Diabetes epidemiology and management 2022-07, Vol.7, p.100082, Article 100082
Main Authors: Caro, Marilyn Katrina C., Cunanan, Elaine C., Kho, Sjoberg A.
Format: Article
Language:English
Subjects:
SGLT2 inhibitors
Type 2 Diabetes
UTI risk factors
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Summary:•Genitourinary infections are quite common among diabetic patients, and some studies suggest that the use of SGLT2 inhibitors further increases this potential risk•The 3 and 6 month incidence of genitourinary infections among type 2 diabetics is higher with dapagliflozin and empagliflozin.•Factors associated with genitourinary infection among Type 2 diabetics on SGLT2 and include HbA1c of ≥7.0%, and concomitant insulin and/or SUR use signifying poorly controlled diabetes. Same factors were linked with genital infection alone, along with diabetes duration of >10 years and overweight/obese BMI. Factors associated with UTI alone include elevated Hba1c and eGFR of
ISSN:2666-9706
2666-9706
DOI:10.1016/j.deman.2022.100082