CD34 + acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax

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Published in:Haematologica (Roma) 2020-08, Vol.105 (8), p.e399-e403
Main Authors: Mattes, Katharina, Gerritsen, Mylène, Folkerts, Hendrik, Geugien, Marjan, van den Heuvel, Fiona A, Svendsen, Arthur Flohr, Yi, Guoqiang, Martens, Joost H A, Vellenga, Edo
Format: Article
Language:English
Subjects:
Bridged Bicyclo Compounds, Heterocyclic - pharmacology
Humans
Leukemia, Myeloid, Acute - drug therapy
Leukemia, Myeloid, Acute - genetics
Online Only
Proto-Oncogene Proteins c-bcl-2 - genetics
Reactive Oxygen Species
Sulfonamides
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container_end_page e403
container_issue 8
container_start_page e399
container_title Haematologica (Roma)
container_volume 105
creator Mattes, Katharina
Gerritsen, Mylène
Folkerts, Hendrik
Geugien, Marjan
van den Heuvel, Fiona A
Svendsen, Arthur Flohr
Yi, Guoqiang
Martens, Joost H A
Vellenga, Edo
description
doi_str_mv 10.3324/haematol.2019.229997
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source Freely Accessible Journals; PubMed Central
subjects Bridged Bicyclo Compounds, Heterocyclic - pharmacology
Humans
Leukemia, Myeloid, Acute - drug therapy
Leukemia, Myeloid, Acute - genetics
Online Only
Proto-Oncogene Proteins c-bcl-2 - genetics
Reactive Oxygen Species
Sulfonamides
title CD34 + acute myeloid leukemia cells with low levels of reactive oxygen species show increased expression of stemness genes and can be targeted by the BCL2 inhibitor venetoclax
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