Unusual painful pelvic masses: Extramedullary hematopoiesis with extramedullary multiple myeloma

Key Clinical Message The coexistence of extramedullary hematopoiesis and extramedullary multiple myeloma can occur and present as painful pelvic masses. In such a case, normal hematopoietic cells may outnumber clonal plasma cells, posing a diagnostic challenge. Computed tomography‐guided biopsy of t...

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Bibliographic Details
Published in:Clinical case reports 2024-05, Vol.12 (5), p.e8890-n/a
Main Authors: Cai, Jennifer, Varda, Marian, Sin, David, Overby, Halline, Yeh, James J.
Format: Article
Language:English
Subjects:
abdominal pain
Biopsy
Blood diseases
Bone marrow
Consent
Editing
extramedullary hematopoiesis
extramedullary multiple myeloma
Hemoglobin
Immunoglobulins
Multiple myeloma
pelvic mass
Plasma
plasma cell
Radiation therapy
Tomography
Writing
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Summary:Key Clinical Message The coexistence of extramedullary hematopoiesis and extramedullary multiple myeloma can occur and present as painful pelvic masses. In such a case, normal hematopoietic cells may outnumber clonal plasma cells, posing a diagnostic challenge. Computed tomography‐guided biopsy of the right iliac fossa mass showing extramedullary hematopoiesis with extramedullary multiple myeloma (A, B; yellow arrow: erythroid island; green arrow: myeloid cell; white arrow: megakaryocyte; black arrows: atypical plasma cells with prominent nucleoli; short black arrow: Dutcher body in an atypical plasma cell). CD61 (C) and CD138 (D) immunohistochemistry stains highlight megakaryocytes and plasma cells, respectively.
ISSN:2050-0904
2050-0904
DOI:10.1002/ccr3.8890