Efficacy of carbomer sodium hyaluronate trehalose vs hyaluronic acid to improve tear film instability and ocular surface discomfort after cataract surgery

To evaluate the effects of carbomer sodium hyaluronate trehalose (CHT) and sodium hyaluronate eye drops on tear film stability and ocular discomfort after cataract surgery. Santa Maria della Misericordia Hospital, Rovigo, Italy. Prospective randomized case-control study. This study enrolled sixty pa...

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Bibliographic Details
Published in:Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2019-07, Vol.13, p.1157-1163
Main Authors: Caretti, L, La Gloria Valerio, A, Piermarocchi, R, Badin, G, Verzola, G, Masarà, F, Scalora, T, Monterosso, C
Format: Article
Language:English
Subjects:
artificial tears
Cataract extraction
cataract surgery
Cataracts
Cytokines
Eye care products
Eye diseases
Eye surgery
Fluorescein
Hyaluronic acid
Medical research
Nonsteroidal anti-inflammatory drugs
Ophthalmic agents
Ophthalmology
Original Research
Patient satisfaction
Proteins
Sodium
tear film instability
trehalose
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Summary:To evaluate the effects of carbomer sodium hyaluronate trehalose (CHT) and sodium hyaluronate eye drops on tear film stability and ocular discomfort after cataract surgery. Santa Maria della Misericordia Hospital, Rovigo, Italy. Prospective randomized case-control study. This study enrolled sixty patients scheduled for unilateral cataract surgery. After phacoemulsification, subjects received carbomer sodium hyaluronate trehalose (trehalose group) or sodium hyaluronate tears (HG group) substitute and were assessed through objective (break up time, corneal and conjunctival staining) and subjective (OSDI questionnaire) clinical evaluations after a two times a day topical administration. Outcome measures were collected preoperatively (baseline), one week (day 7) and 1 month (day 30) after surgery. Finally, each patient was asked to give his personal treatment satisfaction score. Trehalose group showed a steeper break up time (BUT) increase compared to patient treated with hyaluronic acid (
ISSN:1177-5467
1177-5483
1177-5483
DOI:10.2147/opth.s208256