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Scoring systems and outcome of chronic kidney disease patients admitted in intensive care units
The outcome of chronic kidney disease (CKD) patients admitted to the Intensive Care Unit (ICU) is difficult to predict. This study assessed the outcome of CKD patients admitted to the ICU and evaluated prediction of 30-day mortality using the Acute Physiology and Chronic Health Evaluation (APACHE II...
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| Published in: | Saudi journal of kidney diseases and transplantation 2018-03, Vol.29 (2), p.310-317 |
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| container_end_page | 317 |
| container_issue | 2 |
| container_start_page | 310 |
| container_title | Saudi journal of kidney diseases and transplantation |
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| creator | Godhani, Umesh Patel, Mohan Gumber, Manoj Kute, Vivek Goswami, Jitendra Balwani, Manish R. |
| description | The outcome of chronic kidney disease (CKD) patients admitted to the Intensive
Care Unit (ICU) is difficult to predict. This study assessed the outcome of CKD patients admitted to
the ICU and evaluated prediction of 30-day mortality using the Acute Physiology and Chronic
Health Evaluation (APACHE II), Simplified Acute Physiology Score (SAPS II), and Sequential
Organ Failure Assessment (SOFA) score. One hundred consecutive CKD patients admitted to the
ICU at a tertiary care hospital, Ahmedabad between 2011 and 2013 were included prospectively.
Data on demographics, indication for admission, cause of CKD, use of vasoactive drugs and
mechanical ventilation (MV), mode of renal replacement therapy (RRT), and 30-day mortality were
recorded. The APACHE II, SAPS II, and SOFA scores were calculated based on the admission
characteristics. The mean APACHE II, SAPS II, and SOFA scores were 28.22 ± 7.53, 43.04 ±
16.40, and 10.39 ± 5.20, respectively, and area under receiver operating characteristics curve in
predicting 30-day mortality were 0.961, 0.994, and 0.950, respectively. The scores were
significantly higher in 30-day nonsurvivors as compared to survivors (P = 0.001). During the ICU
stay, MV and vasoactive drugs were required in 57% and 67% of the patients, respectively, and the
requirement was significantly greater in nonsurvivors as compared to survivors (P = 0.001). About
85% of patients were on intermittent hemodialysis and 15% of patients were on continuous veno |
| doi_str_mv | 10.4103/1319-2442.229268 |
| format | article |
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Care Unit (ICU) is difficult to predict. This study assessed the outcome of CKD patients admitted to
the ICU and evaluated prediction of 30-day mortality using the Acute Physiology and Chronic
Health Evaluation (APACHE II), Simplified Acute Physiology Score (SAPS II), and Sequential
Organ Failure Assessment (SOFA) score. One hundred consecutive CKD patients admitted to the
ICU at a tertiary care hospital, Ahmedabad between 2011 and 2013 were included prospectively.
Data on demographics, indication for admission, cause of CKD, use of vasoactive drugs and
mechanical ventilation (MV), mode of renal replacement therapy (RRT), and 30-day mortality were
recorded. The APACHE II, SAPS II, and SOFA scores were calculated based on the admission
characteristics. The mean APACHE II, SAPS II, and SOFA scores were 28.22 ± 7.53, 43.04 ±
16.40, and 10.39 ± 5.20, respectively, and area under receiver operating characteristics curve in
predicting 30-day mortality were 0.961, 0.994, and 0.950, respectively. The scores were
significantly higher in 30-day nonsurvivors as compared to survivors (P = 0.001). During the ICU
stay, MV and vasoactive drugs were required in 57% and 67% of the patients, respectively, and the
requirement was significantly greater in nonsurvivors as compared to survivors (P = 0.001). About
85% of patients were on intermittent hemodialysis and 15% of patients were on continuous veno</description><identifier>ISSN: 1319-2442</identifier><identifier>EISSN: 2320-3838</identifier><identifier>DOI: 10.4103/1319-2442.229268</identifier><identifier>PMID: 29657198</identifier><language>eng</language><publisher>Riyadh, Saudi Arabia: Saudi Center for Organ Transplantation</publisher><subject>Age ; Chronic kidney failure ; Critical care ; Failure ; Family medical history ; Health aspects ; Hemodialysis ; Hospital patients ; Hospitals ; Intensive care ; Kidney diseases ; Mortality ; Nephrology ; Patient outcomes ; Physiological aspects ; Physiology ; Population ; Prognosis ; Renal replacement therapy ; Risk factors ; Sepsis ; Transplants & implants</subject><ispartof>Saudi journal of kidney diseases and transplantation, 2018-03, Vol.29 (2), p.310-317</ispartof><rights>COPYRIGHT 2018 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt. Ltd. Mar/Apr 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c668s-2703e34b7f58262c3372aa8b846c8be47268af0f2a56aef85f67f26a376b4b2e3</citedby><cites>FETCH-LOGICAL-c668s-2703e34b7f58262c3372aa8b846c8be47268af0f2a56aef85f67f26a376b4b2e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/2025624196?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,25753,27924,27925,37012,37013,44590</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29657198$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Godhani, Umesh</creatorcontrib><creatorcontrib>Patel, Mohan</creatorcontrib><creatorcontrib>Gumber, Manoj</creatorcontrib><creatorcontrib>Kute, Vivek</creatorcontrib><creatorcontrib>Goswami, Jitendra</creatorcontrib><creatorcontrib>Balwani, Manish R.</creatorcontrib><title>Scoring systems and outcome of chronic kidney disease patients admitted in intensive care units</title><title>Saudi journal of kidney diseases and transplantation</title><addtitle>Saudi J Kidney Dis Transpl</addtitle><description>The outcome of chronic kidney disease (CKD) patients admitted to the Intensive
Care Unit (ICU) is difficult to predict. This study assessed the outcome of CKD patients admitted to
the ICU and evaluated prediction of 30-day mortality using the Acute Physiology and Chronic
Health Evaluation (APACHE II), Simplified Acute Physiology Score (SAPS II), and Sequential
Organ Failure Assessment (SOFA) score. One hundred consecutive CKD patients admitted to the
ICU at a tertiary care hospital, Ahmedabad between 2011 and 2013 were included prospectively.
Data on demographics, indication for admission, cause of CKD, use of vasoactive drugs and
mechanical ventilation (MV), mode of renal replacement therapy (RRT), and 30-day mortality were
recorded. The APACHE II, SAPS II, and SOFA scores were calculated based on the admission
characteristics. The mean APACHE II, SAPS II, and SOFA scores were 28.22 ± 7.53, 43.04 ±
16.40, and 10.39 ± 5.20, respectively, and area under receiver operating characteristics curve in
predicting 30-day mortality were 0.961, 0.994, and 0.950, respectively. The scores were
significantly higher in 30-day nonsurvivors as compared to survivors (P = 0.001). During the ICU
stay, MV and vasoactive drugs were required in 57% and 67% of the patients, respectively, and the
requirement was significantly greater in nonsurvivors as compared to survivors (P = 0.001). About
85% of patients were on intermittent hemodialysis and 15% of patients were on continuous veno</description><subject>Age</subject><subject>Chronic kidney failure</subject><subject>Critical care</subject><subject>Failure</subject><subject>Family medical history</subject><subject>Health aspects</subject><subject>Hemodialysis</subject><subject>Hospital patients</subject><subject>Hospitals</subject><subject>Intensive care</subject><subject>Kidney diseases</subject><subject>Mortality</subject><subject>Nephrology</subject><subject>Patient outcomes</subject><subject>Physiological aspects</subject><subject>Physiology</subject><subject>Population</subject><subject>Prognosis</subject><subject>Renal replacement therapy</subject><subject>Risk factors</subject><subject>Sepsis</subject><subject>Transplants & implants</subject><issn>1319-2442</issn><issn>2320-3838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkl1rFDEUhgdR7Fq990YZEMSbXTP5msxlKX4UCl6o1yGbnOymnUlqkum6_95sZ7q2IhMYSJ7znpzwVNXrBq1og8jHhjTdElOKVxh3mIsn1QITjJZEEPG0WhyPT6oXKV0hxFjH-fPqBHectU0nFpX8rkN0flOnfcowpFp5U4cx6zBAHWyttzF4p-trZzzsa-MSqAT1jcoOfC64GVzOYGrny8rgk7uFWqsI9ehdTi-rZ1b1CV7N_9Pq5-dPP86_Li-_fbk4P7tcas5FWuIWESB03VomMMeakBYrJdaCci3WQNsynLLIYsW4AiuY5a3FXJGWr-kaAzmtLqZcE9SVvIluUHEvg3LybiPEjVQxO92DJMa0HcbcNhpTY4kQYDRQLTiliHFTsj5MWTcx_BohZTm4pKHvlYcwJokRZgI1TLCCvvsHvQpj9GXSO4pj2nT8L7VRpb_zNuSo9CFUnjFCO9Qi0RZq9R-qfAYGp4MH68r-o4L3Dwq2oPq8TaEfsws-PQbRBOoYUopgjw_UIHkQSR5MkQdT5CRSKXk7DzauBzDHgntzCvB7AnahzxDTdT_uIMrCXvuwexS8fBAsSTmZnZOzc7I4J2fnZLBydk5OzsnZOXnvXGn9ZmoN5Upg1fFyxXrWMPIHcCD1ew</recordid><startdate>20180301</startdate><enddate>20180301</enddate><creator>Godhani, Umesh</creator><creator>Patel, Mohan</creator><creator>Gumber, Manoj</creator><creator>Kute, Vivek</creator><creator>Goswami, Jitendra</creator><creator>Balwani, Manish R.</creator><general>Saudi Center for Organ Transplantation</general><general>Wolters Kluwer India Pvt. 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Care Unit (ICU) is difficult to predict. This study assessed the outcome of CKD patients admitted to
the ICU and evaluated prediction of 30-day mortality using the Acute Physiology and Chronic
Health Evaluation (APACHE II), Simplified Acute Physiology Score (SAPS II), and Sequential
Organ Failure Assessment (SOFA) score. One hundred consecutive CKD patients admitted to the
ICU at a tertiary care hospital, Ahmedabad between 2011 and 2013 were included prospectively.
Data on demographics, indication for admission, cause of CKD, use of vasoactive drugs and
mechanical ventilation (MV), mode of renal replacement therapy (RRT), and 30-day mortality were
recorded. The APACHE II, SAPS II, and SOFA scores were calculated based on the admission
characteristics. The mean APACHE II, SAPS II, and SOFA scores were 28.22 ± 7.53, 43.04 ±
16.40, and 10.39 ± 5.20, respectively, and area under receiver operating characteristics curve in
predicting 30-day mortality were 0.961, 0.994, and 0.950, respectively. The scores were
significantly higher in 30-day nonsurvivors as compared to survivors (P = 0.001). During the ICU
stay, MV and vasoactive drugs were required in 57% and 67% of the patients, respectively, and the
requirement was significantly greater in nonsurvivors as compared to survivors (P = 0.001). About
85% of patients were on intermittent hemodialysis and 15% of patients were on continuous veno</abstract><cop>Riyadh, Saudi Arabia</cop><pub>Saudi Center for Organ Transplantation</pub><pmid>29657198</pmid><doi>10.4103/1319-2442.229268</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Saudi journal of kidney diseases and transplantation, 2018-03, Vol.29 (2), p.310-317 |
| issn | 1319-2442 2320-3838 |
| language | eng |
| recordid | cdi_doaj_primary_oai_doaj_org_article_3dd79226f1c24df388edce4c8644056d |
| source | Publicly Available Content Database; Medknow Medical Journals (Open access) |
| subjects | Age Chronic kidney failure Critical care Failure Family medical history Health aspects Hemodialysis Hospital patients Hospitals Intensive care Kidney diseases Mortality Nephrology Patient outcomes Physiological aspects Physiology Population Prognosis Renal replacement therapy Risk factors Sepsis Transplants & implants |
| title | Scoring systems and outcome of chronic kidney disease patients admitted in intensive care units |
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