High Monocyte-to-Lymphocyte Ratio is Associated with Obstructive Sleep Apnea Hypopnea Syndrome

This study aims to explore the correlation between serum monocyte-to-lymphocyte ratio (MLR) and other inflammatory parameters with the occurrence of obstructive sleep apnea-hypopnea syndrome (OSAHS) in patients. This study included 310 patients who underwent polysomnography monitoring at our hospita...

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Bibliographic Details
Published in:Journal of inflammation research 2024-01, Vol.17, p.2137-2145
Main Authors: Bao, Wenyu, Gao, Junkang, Fang, Siyu, Zhang, Shiwei, Wan, Yufeng
Format: Article
Language:English
Subjects:
Comparative analysis
Inflammation
Lymphocytes
Medical research
Medicine, Experimental
monocyte to lymphocyte ratio
obstructive sleep apnea hypopnea syndrome
polysomnography
Risk factors
Sleep apnea syndromes
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Summary:This study aims to explore the correlation between serum monocyte-to-lymphocyte ratio (MLR) and other inflammatory parameters with the occurrence of obstructive sleep apnea-hypopnea syndrome (OSAHS) in patients. This study included 310 patients who underwent polysomnography monitoring at our hospital between January 2021 and January 2023. Routine blood inflammatory parameters and polysomnography (PSG) results were also evaluated. The differences in inflammatory markers between the OSAHS and normal groups were compared, and OSAHS independent related factors were screened. The MLR of OSAHS group was significantly higher than that of control group, and the difference was statistically significant. Multivariate logistic regression analysis suggested that MLR is an independent risk factor for OSAHS. High MLR was correlated with OSAHS. The diagnostic value of MLR was better than that of the other inflammatory parameters.
ISSN:1178-7031
1178-7031
DOI:10.2147/JIR.S455559