Using MEST-C Scores and the International Study of Kidney Disease in Children Classification to Predict Outcomes of Henoch-Schönlein Purpura Nephritis in Children

Henoch-Schönlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) bear similarities in some aspects. The histological classification of HSPN was built on the International Study of Kidney Disease in Children (ISKDC) criteria, while IgAN was established on the 2016 Oxford classification (MEST-C sc...

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Bibliographic Details
Published in:Frontiers in pediatrics 2021-04, Vol.9, p.658845-658845
Main Authors: Wang, Meiqiu, Wang, Ren, He, Xu, Zhang, Pei, Kuang, Qianhuining, Yao, Jun, Fang, Xiang, Shi, Zhuo, Wu, Heyan, Peng, Yingchao, Xia, Zhengkun, Gao, Chunlin
Format: Article
Language:English
Subjects:
Henoch–Schönlein purpura nephritis
IgA vasculitis
ISKDC classification
MEST-C score
Oxford classification
Pediatrics
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Summary:Henoch-Schönlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) bear similarities in some aspects. The histological classification of HSPN was built on the International Study of Kidney Disease in Children (ISKDC) criteria, while IgAN was established on the 2016 Oxford classification (MEST-C scores). The purpose of this paper was to discuss the predictive value of the ISKDC classification and MEST-C scores in children with HSPN. We performed a retrospective study of 877 children with HSPN in a single center between 2001 and 2019. The primary outcome was defined as chronic kidney disease-estimated glomerular filtration rate (eGFR)
ISSN:2296-2360
2296-2360
DOI:10.3389/fped.2021.658845